POU2AF1 抗体 (C-Term)
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北京 101111
Quick Overview for POU2AF1 抗体 (C-Term) (ABIN3044424)
抗原
See all POU2AF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-BOB1/POU2AF1 Antibody
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序列
- EEEESNTYEL NHTLSVEGF
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related rat sequence by one amino acid,and from human sequence by four amino acids.
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产品特性
- Anti-BOB1/POU2AF1 Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse BOB1, different from the related rat sequence by one amino acid, and from human sequence by four amino acids.
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亚型
- IgG
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anti-POU Class 2 Associating Factor 1 (POU2AF1) (AA 148-255) antibody
POU2AF1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal BOB1-2424 unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (AA 148-255) antibodyPOU2AF1 适用: 人 WB, IHC, FACS 宿主: 小鼠 Monoclonal BOB1-2421 unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (AA 1-27), (N-Term) antibodyPOU2AF1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22378 unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (C-Term) antibodyVerified POU2AF1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) antibodyPOU2AF1 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 4A5 unconjugated Recombinant Antibody
anti-POU Class 2 Associating Factor 1 (POU2AF1) (C-Term) antibodyVerified POU2AF1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (C-Term) antibodyPOU2AF1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) antibodyPOU2AF1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) antibodyPOU2AF1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1715 unconjugated Recombinant Antibody
anti-POU Class 2 Associating Factor 1 (POU2AF1) antibodyPOU2AF1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB13345 unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, MouseWestern blot, 0.1-0.5 μg/mL, Mouse
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))
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别名
- POU2AF1
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背景
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Background: POU2AF1 (POU domain class 2-associating factor 1), also known as OBF1, BOB1 and OCAB, is a protein that in humans is encoded by the POU2AF1 gene. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is additionally conferred at the dimerization level. Casellas et al. (2002) reported that OCAB is essential for V (D)J recombination of a subset of Ig-kappa genes. They showed that OCAB modulates recombination by ly enhancing Ig-kappa gene transcription in vivo. Siegel et al. (2006) suggested that, together with dysregulation of other OCAB target genes, altered regulation of SYK may help explain the magnitude of defects observed in B-cell development, including the pre-B1-to-pre-B2 transition, and immune responses in Ocab -/- mice.
Gene Full Name: POU domain, class 2, associating factor 1
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分子量
- 37 kDa
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基因ID
- 18985
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UniProt
- Q64693
抗原
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