MTA1 抗体 (C-Term)
Quick Overview for MTA1 抗体 (C-Term) (ABIN3044412)
抗原
See all MTA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 676-696, C-Term
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原理
- Anti-MTA1 Antibody Picoband®
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序列
- ETKRAARRPY KPIALRQSQA L
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MTA1 Antibody (ABIN3044412). Tested in IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MTA1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibody
MTA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibodyMTA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D5 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibodyMTA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 541-715) antibodyMTA1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B1E9 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-715) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) antibodyMTA1 适用: 人 IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 541-715) antibodyMTA1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G9C10 unconjugated
anti-Metastasis Associated 1 (MTA1) (Internal Region) antibodyVerified MTA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (Internal Region) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 659-687), (C-Term) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB40949 unconjugated
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应用备注
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Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse, Rat, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Cui, Q., Takiguchi, S., Matsusue, K., Toh, Y., Yoshida, M. A.Assignment of the human metastasis-associated gene 1 (MTA1) to human chromosome band 14q32.3 by fluorescence in situ hybridization. Cytogenet. Cell Genet. 93: 139-140, 2001. 2. Reddy, S. D. N., Pakala, S. B., Ohshiro, K., Rayala, S. K., Kumar, R.MicroRNA-661, a c/EBP-alpha target, inhibits metastatic tumor antigen 1 and regulates its functions.Cancer Res. 69: 5639-5642, 2009. 3. Zhang, X., DeSalle, L. M., Patel, J. H., Capobianco, A. J., Yu, D., Thomas-Tikhonenko, A., McMahon, S. B.Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein.Proc. Nat. Acad. Sci. 102: 13968-13973, 2005. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- MTA1 (Metastasis Associated 1 (MTA1))
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别名
- MTA1
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背景
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Synonyms: Metastasis-associated protein MTA1,MTA1,
Tissue Specificity: Widely expressed. High expression in brain, liver, kidney, and cardiac muscle, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual. Up-regulated in a wide variety of cancers including breast, liver, ovarian, and colorectal cancer and its expression levels are closely correlated with tumor aggressiveness and metastasis. .
Background: Metastasis-associated protein MTA1 is a protein that in humans is encoded by the MTA1 gene. This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues.By fluorescence in situ hybridization, mapped the MTA1gene to chromosome 14q32.3. MTA1 is a component of the chromatin remodeling complex that influences gene transcription by modulating target gene chromatin. MTA1 is widely upregulated in many carcinomas.
Sequence Similarities: Contains 1 BAH domain.
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分子量
- 80 kDa
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UniProt
- Q13330
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途径
- Chromatin Binding
抗原
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