FGF19 抗体 (Middle Region)
Quick Overview for FGF19 抗体 (Middle Region) (ABIN3044409)
抗原
See all FGF19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-140, Middle Region
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原理
- Anti-Fibroblast growth factor 19 FGF19 Antibody Picoband®
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序列
- EEIRPDGYNV YRSEKHR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Fibroblast growth factor 19 FGF19 Antibody (ABIN3044409). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human FGF19.
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亚型
- IgG
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anti-Fibroblast Growth Factor 19 (FGF19) (AA 4-216) antibody
FGF19 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) (AA 1-216) antibodyFGF19 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) (AA 25-216) antibodyFGF19 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) (AA 25-216) antibodyFGF19 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) (C-Term) antibodyFGF19 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) (AA 1-216) antibodyFGF19 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) antibodyFGF19 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal FG369-1 unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) (AA 1-216) antibodyFGF19 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fibroblast Growth Factor 19 (FGF19) antibodyFGF19 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal FG98-6 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Kir, S., Beddow, S. A., Samuel, V. T., Miller, P., Previs, S. F., Suino-Powell, K., Xu, H. E., Shulman, G. I., Kliewer, S. A. , Mangelsdorf, D. J.FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis. 2. Ladher, R. K., Anakwe, K. U., Gurney, A. L., Schoenwolf, G. C., Francis-West, P. H.Identification of synergistic signals initiating inner ear development. 3. Nishimura, T., Utsunomiya, Y., Hoshikawa, M., Ohuchi, H., Itoh, N.Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain. Biochim. Biophys. Acta 1444: 148-151, 1999. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- FGF19 (Fibroblast Growth Factor 19 (FGF19))
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别名
- FGF19
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背景
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Synonyms: Fibroblast growth factor 19,FGF-19,FGF19,UNQ334/PRO533,
Tissue Specificity: Expressed in fetal brain, cartilage, retina, and adult gall bladder. .
Background: FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity.
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分子量
- 24 kDa
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UniProt
- O95750
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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