GDNF 抗体 (Middle Region)
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北京 101111
Quick Overview for GDNF 抗体 (Middle Region) (ABIN3044406)
抗原
See all GDNF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-GDNF Antibody
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序列
- FRYCSGSCDA AETTYDK
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by three amino acids,rat sequence by two amino acids.
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产品特性
- Anti-GDNF Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of < a href=https://www.bosterbio.com/human-gdnf-picokine-trade-elisa-kit-ek0362-boster.html style=color:#EA8D28>human GDNF, different from the related mouse sequence by three amino acids and rat sequence by two amino acids.
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亚型
- IgG
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anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 121-211) antibody
GDNF 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, FACS, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) antibodyGDNF 适用: 人 WB, IHC, IP, FACS, ELISA 宿主: 兔 Monoclonal 11D2 unconjugated Recombinant Antibody
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 192-207), (C-Term) antibodyGDNF 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 8-36) antibodyGDNF 适用: 人, 小鼠 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 121-211) antibody (FITC)GDNF 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, FACS, IF (p), IF (cc) 宿主: 兔 Polyclonal FITC
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) antibodyGDNF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 79-217) antibodyGDNF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) antibodyGDNF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 8-36), (N-Term) antibodyGDNF 适用: 人 FACS, IHC (p) 宿主: 兔 Polyclonal RB21995 unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) antibodyGDNF 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB3395 unconjugated Recombinant Antibody
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Surface functionalization of TiO2 nanotubes with minocycline and its in vitro biological effects on Schwann cells." in: Biomedical engineering online, Vol. 17, Issue 1, pp. 88, (2018) (PubMed).
: "Lipopolysaccharide inhibits the self-renewal of spermatogonial stem cells in vitro via downregulation of GDNF expression in Sertoli cells." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 45, pp. 87-93, (2014) (PubMed).
: "Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction." in: Neural regeneration research, Vol. 8, Issue 23, pp. 2190-7, (2014) (PubMed).
: "S100B protein, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in human milk." in: PLoS ONE, Vol. 6, Issue 6, pp. e21663, (2011) (PubMed).
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- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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别名
- GDNF
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背景
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Background: GDNF, Glial cell-derived neurotrophic factor, is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small protein that potently promotes the survival of many types of neurons. GDNF is a founding member of the GDNF family of ligands (GFL). The GDNF gene is mapped to human chromosome 5p13.1-p12 by fluorescence in situ hybridization (FISH). This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosisof motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene.
Gene Full Name: glial cell derived neurotrophic factor
Sequence Similarities: Belongs to the TGF-beta family. GDNF subfamily.
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分子量
- 24 kDa
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基因ID
- 2668
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UniProt
- P39905
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途径
- RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
抗原
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