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- 抗原 See all FGF21 抗体
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
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抗原表位
- AA 43-58, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGF21 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Fibroblast growth factor 21(FGF21) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- QVRQRYLYTD DAQQTE
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Fibroblast growth factor 21(FGF21) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: fibroblast growth factor 21
Protein Name: Fibroblast growth factor 21(FGF-21) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human FGF21(43-58aa QVRQRYLYTDDAQQTE), different from the related rat and mouse sequences by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product FGF21 Primary Antibody
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anti-Fibroblast Growth Factor 21 (FGF21) (AA 30-209) antibody
FGF21 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) antibodyFGF21 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (AA 30-209) antibodyFGF21 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (AA 29-209) antibodyFGF21 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (AA 29-209) antibodyFGF21 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (N-Term) antibodyFGF21 适用: 人, 小鼠, 大鼠, Pig, 猴, 马, Cow, 犬, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (Internal Region) antibodyVerified FGF21 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (AA 29-120) antibodyFGF21 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (AA 29-209) antibodyFGF21 适用: 人 FACS 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 21 (FGF21) (AA 29-209) antibodyFGF21 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Predicted Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- FGF21 (Fibroblast Growth Factor 21 (FGF21))
- 别名
- FGF21 (FGF21 产品)
- 别名
- FGF21 antibody, fibroblast growth factor 21 antibody, FGF21 antibody, fgf21 antibody, Fgf21 antibody
- 背景
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FGF21(Fibroblast growth factor 21) is a protein that in humans is encoded by the FGF21 gene, which is also a member of the fibroblast growth factor(FGF) family. The FGF21 gene is mapped on 19q13.33. Using RT-PCR, Fgf21 was expressed in several types of adipose tissue in mice, including subcutaneous and epididymal fat pads and brown adipose tissue. The level of Fgf21 expression in adipose tissue was comparable to that in liver. FGF21 stimulates glucose uptake in adipocytes but not in other cell types. This effect is additive to the activity of insulin. FGF21 treatment of adipocytes is associated with phosphorylation of FRS2, a protein linking FGF receptors to the Ras/MAP kinase pathway. FGF21 also protects animals from diet-induced obesity when overexpressed in transgenic mice and lowers blood glucose and triglyceride levels when administered to diabetic rodents. Changes in Fgf21 expression due to suckling or nutritional manipulations were associated with changes in circulating free fatty acid and ketone body levels. In differentiated mouse brown adipocytes in culture, Fgf21 treatment increased the expression of thermogenic genes, caused higher total and uncoupled respiration, and enhanced glucose oxidation.
Synonyms: FGF 21 antibody|FGF-21 antibody|Fgf21 antibody|FGF21_HUMAN antibody|FGFL antibody|Fibroblast growth factor 21 antibody|PRO10196 antibody|UNQ3115 antibody - 途径
- RTK signaling
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