MCM5 抗体 (C-Term)
Quick Overview for MCM5 抗体 (C-Term) (ABIN3044244)
抗原
See all MCM5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 720-734, C-Term
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原理
- Anti-MCM5 Antibody Picoband®
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序列
- EIQHRMQRKV LYRLK
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MCM5 Antibody (ABIN3044244). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MCM5, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Minichromosome Maintenance Complex Component 5 (MCM5) antibody
MCM5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) (N-Term) antibodyMCM5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) (AA 331-537) antibodyMCM5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) (AA 1-230) antibodyMCM5 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) antibodyMCM5 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) (AA 1-230) antibodyMCM5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) (N-Term) antibodyMCM5 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) antibodyMCM5 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CRCT5-1 unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) antibodyMCM5 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal CRCT5-1 unconjugated
anti-Minichromosome Maintenance Complex Component 5 (MCM5) (N-Term) antibodyMCM5 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Burkhart, R., Schulte, D., Hu, D., Musahl, C., Gohring, F., Knippers, R. Interactions of human nuclear proteins P1Mcm3 and P1Cdc46. Europ. J. Biochem. 228: 431-438, 1995. 2. Groth, A., Corpet, A., Cook, A. J. L., Roche, D., Bartek, J., Lukas, J., Almouzni, G. Regulation of replication fork progression through histone supply and demand. Science 318: 1928-1931, 2007. 3. Paul R, Hu B, Musahl C, Hameister H, Knippers R (Sep 1996). "Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5". Cytogenet Cell Genet 73 (4): 317-21. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
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别名
- MCM5
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背景
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Synonyms: DNA replication licensing factor MCM5,3.6.4.12,CDC46 homolog,P1-CDC46,MCM5,CDC46,
Tissue Specificity: Heart, liver, duodenum, blood vessels and kidney.
Background: MCM5 (MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 5),also known as CDC46, is a protein that in humans is encoded by the MCM5 gene. MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. And MCM5 is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The MCM5 gene is mapped on 22q12.3. The MCM5 gene contains 16 exons. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Sequence Similarities: Belongs to the MCM family.
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分子量
- 82 kDa
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UniProt
- P33992
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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