Peroxiredoxin 3 抗体 (C-Term)
-
- 抗原 See all Peroxiredoxin 3 (PRDX3) 抗体
- Peroxiredoxin 3 (PRDX3)
-
抗原表位
- AA 239-256, C-Term
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Peroxiredoxin 3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Thioredoxin-dependent peroxide reductase, mitochondrial(PRDX3) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 序列
- TIKPSPAASK EYFQKVNQ
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Thioredoxin-dependent peroxide reductase, mitochondrial(PRDX3) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: peroxiredoxin 3
Protein Name: Thioredoxin-dependent peroxide reductase, mitochondrial - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Peroxiredoxin 3(239-256aa TIKPSPAASKEYFQKVNQ), different from the related mouse and rat sequences by three amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PRDX3 Primary Antibody
-
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibody
PRDX3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 5-233) antibodyPRDX3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 63-256) antibodyPRDX3 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibodyPRDX3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 110-256) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 239-256) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 1-256) antibodyPRDX3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 1E3-B2 unconjugated
anti-Peroxiredoxin 3 (PRDX3) (AA 110-256) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peroxiredoxin 3 (PRDX3) antibodyPRDX3 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
-
- 抗原
- Peroxiredoxin 3 (PRDX3)
- 别名
- PRDX3 (PRDX3 产品)
- 背景
-
PRDX3(peroxiredoxin 3) also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human AOP1 protein shares 86 % amino acid sequence similarity with mouse Aop1, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that PRDX3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells. These data provided evidence that PRDX3 is a MYC target gene that is required to maintain normal mitochondrial function.
Synonyms: Antioxidant Protein 1 antibody|AOP 1 antibody|AOP-1 antibody|AOP1 antibody|HBC189 antibody|MER 5 antibody|MER5 antibody|MGC104387 antibody|MGC24293 antibody|mitochondrial antibody|Mitochondrial thioredoxin dependent peroxide reductase antibody|peroxiredoxin 3 antibody|PeroxiredoxinIII antibody|Peroxiredoxin-3 antibody|Peroxiredoxin3 antibody|PRDX 3 antibody|PRDX3 antibody|PRDX3_HUMAN antibody|PRO1748 antibody|Protein MER5 homolog antibody|PRX III antibody|PRXIII antibody|Prx-III antibody|PRX3 antibody|SP 22 antibody|SP-22 antibody|SP22 antibody|Thioredoxin dependent peroxide reductase mitochondrial antibody|Thioredoxin dependent peroxide reductase precursor antibody|Thioredoxin-dependent peroxide reductase antibody - UniProt
- P30048
- 途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
-
