(1 reference)-
- 抗原 See all GLI3 抗体
- GLI3 (GLI Family Zinc Finger 3 (GLI3))
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抗原表位
- AA 40-57, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLI3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Transcriptional activator GLI3(GLI3) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- SNEDESPGQT YHRERRNA
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Transcriptional activator GLI3(GLI3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: GLI family zinc finger 3
Protein Name: Transcriptional activator GLI3 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Gli3(40-57aa SNEDESPGQTYHRERRNA), different from the related rat sequence by two amino acids, and from the related mouse sequence by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product GLI3 Primary Antibody
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anti-GLI Family Zinc Finger 3 (GLI3) antibody
GLI3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 3 (GLI3) (AA 1-110) antibodyGLI3 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-GLI Family Zinc Finger 3 (GLI3) (AA 30-60) antibodyGLI3 适用: 人 WB, ELISA, IHC, IF, FM, MA 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 3 (GLI3) (AA 1-110) antibodyGLI3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-GLI Family Zinc Finger 3 (GLI3) (AA 1-110) antibodyGLI3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H7 unconjugated
anti-GLI Family Zinc Finger 3 (GLI3) (AA 800-900) antibodyGLI3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 3 (GLI3) (AA 11-60) antibodyGLI3 适用: 人, 小鼠, 大鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 3 (GLI3) (N-Term) antibodyGLI3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "Anti-apoptotic role of sonic hedgehog on blood platelets." in: Thrombosis research, Vol. 134, Issue 6, pp. 1311-5, (2014) (PubMed).
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: "Anti-apoptotic role of sonic hedgehog on blood platelets." in: Thrombosis research, Vol. 134, Issue 6, pp. 1311-5, (2014) (PubMed).
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- 抗原
- GLI3 (GLI Family Zinc Finger 3 (GLI3))
- 别名
- GLI3 (GLI3 产品)
- 背景
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GLI3(Gli-kruppel family member 3), also called ONCOGENE GLI3, encodes a member of the zinc finger gene family related to Kruppel, a gene that is known to regulate development in Drosophila. The GLI3 gene is expressed as an 8.5-kb mRNA in tissues such as testis, myometrium, placenta, and lung, and the protein product(relative molecular mass, 190,000) shows sequence-specific DNA binding. The GLI3 gene is mapped on 7p14.1. GLI3 is homologous to the Drosophila cubitus interruptus(ci) gene product(Ci), which regulates the Patched(pct), gooseberry(gsb), and decapentaplegic(dpp) genes. PKA-dependent processing of vertebrate GLI3 in developing limb generates a potent repressor in a manner antagonized by apparent long-range signaling from posteriorly localized Sonic hedgehog protein. The high relative abundance and potency of GLI3 repressor suggested specialization of GLI3 and its products for negative hedgehog pathway regulation.Coimmunoprecipitation and immunoblot studies showed that GLI3 protein is polyubiquitinated and that its processing depends on proteasome activity. The findings suggested that BTRC is required for GLI3 processing.
Synonyms: ACLS antibody|DNA binding protein antibody|GCPS antibody|Gli 3 antibody|GLI family zinc finger 3 antibody|GLI Kruppel family member GLI 3 antibody|GLI Kruppel family member GLI3(Greig cephalopolysyndactyly syndrome) antibody|GLI Kruppel family member GLI3 antibody|GLI3 antibody|GLI3 C-terminally truncated form antibody|GLI3 form of 190 kDa antibody|GLI3 form of 83 kDa antibody|GLI3 full length protein antibody|GLI3-190 antibody|GLI3-83 antibody|GLI3_HUMAN antibody|GLI3FL antibody|Glioma associated oncogene family zinc finger 3 antibody|Oncogene GLI3 antibody|PAP A antibody|PAPA 1 antibody|PAPA antibody|PAPA1 antibody|PAPB antibody|PHS antibody|PPD IV antibody|PPDIV antibody|Transcriptional activator GLI3 antibody|Transcriptional repressor GLI3R antibody|Zinc finger protein GLI 3 antibody|Zinc finger protein GLI3 antibody - UniProt
- P10071
- 途径
- Hedgehog Signaling
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