Glutaredoxin 2 抗体 (Middle Region)
Quick Overview for Glutaredoxin 2 抗体 (Middle Region) (ABIN3044103)
抗原
See all Glutaredoxin 2 (GRX2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 103-119, Middle Region
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原理
- Anti-Glutaredoxin 2/GLRX2 Antibody Picoband®
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序列
- EYGNQFQDAL YKMTGER
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Glutaredoxin 2/GLRX2 Antibody (ABIN3044103). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Glutaredoxin 2, different from the related rat sequence by two amino acids, and from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibody
GRX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 120-146), (C-Term) antibodyGRX2 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18221 unconjugated
anti-Glutaredoxin 2 (GRX2) (Middle Region) antibodyGRX2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 126-155), (C-Term) antibodyGRX2 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 101-164) antibodyGRX2 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-164) antibodyGRX2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 91-141) antibodyGRX2 适用: 人, Cow, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
1. Gladyshev, V. N., Liu, A., Novoselov, S. V., Krysan, K., Sun, Q.-A., Kryukov, V. M., Kryukov, G. V., Lou, M. F.Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2.J. Biol. Chem. 276: 30374-30380, 2001. 2. Lilig, C. H., Berndt, C., Vergnolle, O., Lonn, M. E., Hudemann, C., Bill, E., Holmgren, A.Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor.Proc. Nat. Acad. Sci. 102: 8168-8173, 2005. 3. Lundberg, M., Johansson, C., Chandra, J., Enoksson, M., Jacobsson, G., Ljung, J., Johansson, M., Holmgren, A.Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms.J. Biol. Chem. 276: 26269-26275, 2001. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.01 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Glutaredoxin 2 (GRX2)
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别名
- GLRX2
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背景
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Synonyms: Glutaredoxin-2, mitochondrial,GLRX2,GRX2,CGI-133,
Tissue Specificity: Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta and lung. Not expressed in peripheral blood leukocytes. .
Background: GLRX2 (Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins (e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al. (2001) and Gladyshev et al. (2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al. (2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon (exon 1B) located upstream from the first exon used by the GLRX2A transcript (exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al. (2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.
Sequence Similarities: Belongs to the glutaredoxin family.
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分子量
- 18 kDa
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途径
- Cell RedoxHomeostasis
抗原
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