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Glutaredoxin 2 抗体 (AA 1-124)

GRX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7154050
发货至: 中国
  • 抗原 See all Glutaredoxin 2 (GRX2) 抗体
    Glutaredoxin 2 (GRX2)
    抗原表位
    • 16
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-124
    适用
    • 40
    • 23
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 34
    • 6
    克隆类型
    • 38
    • 2
    多克隆
    标记
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glutaredoxin 2 antibody is un-conjugated
    应用范围
    • 34
    • 21
    • 13
    • 13
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Glutaredoxin-2, mitochondrial protein (1-124AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Glutaredoxin 2 (GRX2)
    别名
    GLRX2 (GRX2 产品)
    别名
    ECK1049 antibody, JW1051 antibody, CGI-133 antibody, GRX2 antibody, 1700010P22Rik antibody, AI645710 antibody, Grx2 antibody, glutaredoxin 2 (Grx2) antibody, glutaredoxin Grx2 antibody, thioredoxin antibody, glutaredoxin 2 antibody, glutaredoxin 2 (thioltransferase) antibody, grxB antibody, grx2 antibody, AF_RS10790 antibody, GLRX2 antibody, Glrx2 antibody
    背景

    Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

    Aliases: bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2) antibody, bA101E13.1 antibody, CGI133 antibody, Glrx2 antibody, GLRX2_HUMAN antibody, Glutaredoxin-2 antibody, Glutaredoxin-2, mitochondrial antibody, GRX2 antibody, mitochondrial antibody

    UniProt
    Q9NS18
    途径
    Cell RedoxHomeostasis
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