Glutaredoxin 2 抗体 (Middle Region)
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北京 101111
Quick Overview for Glutaredoxin 2 抗体 (Middle Region) (ABIN2787395)
抗原
See all Glutaredoxin 2 (GRX2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- GLRX2 Antibody - middle region
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序列
- NVNYKVVELD LLEYGNQFQD ALYKMTGERT VPRIFVNGTF IGGATDTHRL H
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预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against GLRX2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GLRX2
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anti-Glutaredoxin 2 (GRX2) (AA 1-164) antibody
GRX2 适用: 人, 小鼠 WB, FACS, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 120-146), (C-Term) antibodyGRX2 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18221 unconjugated
anti-Glutaredoxin 2 (GRX2) (Internal Region) antibodyGRX2 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 101-164) antibodyGRX2 适用: 人 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 126-155), (C-Term) antibodyGRX2 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 91-141) antibodyGRX2 适用: 人, Cow, 犬, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Glutaredoxin 2 (GRX2) (AA 1-124) antibodyGRX2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57792-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Glutaredoxin 2 (GRX2)
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别名
- GLRX2
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背景
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Background Information: GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression of GLRX2 decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Gene Name: Glutaredoxin 2
Alternative Symbols: GRX2, CGI-133
Protein Name: Glutaredoxin-2, mitochondrial
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分子量
- 18kDa
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基因ID
- 51022
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NCBI登录号
- NP_932066
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UniProt
- Q9NS18
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途径
- Cell RedoxHomeostasis
抗原
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