p63 抗体 (C-Term)
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- 抗原 See all p63 (TP63) 抗体
- p63 (TP63) (Tumor Protein P63 (TP63))
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抗原表位
- AA 664-680, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This p63 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Anti-p63/TP63 Antibody Picoband®
- 序列
- DMDARRNKQQ RIKEEGE
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-p63/TP63 Antibody (ABIN3044067). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human p63, different from the related rat and mouse sequences by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product TP63 Primary Antibody
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anti-Tumor Protein P63 (TP63) antibody
KO Validated TP63 适用: 人 WB, ICC, IF, IP, IHC (p), IHC (fro), PLA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 5-17) antibodyTP63 适用: 人, 小鼠, 大鼠, Cow WB, IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TP63-2428 unconjugated
anti-Tumor Protein P63 (TP63) (AA 3-106) antibodyTP63 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TP63-1786 unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠 IHC, StM 宿主: 小鼠 Monoclonal TP63-11 unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (C-Term) antibodyTP63 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (N-Term) antibodyTP63 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (pSer455) antibodyTP63 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 4B3 unconjugated Recombinant Antibody
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- 应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Hibi, K., Trink, B., Patturajan, M., Westra, W. H., Caballero, O. L., Hill, D. E., Ratovitski, E. A., Jen, J., Sidransky, D. AIS is an oncogene amplified in squamous cell carcinoma. Proc. Nat. Acad. Sci. 97: 5462-5467, 2000. 2. Osada, M., Ohba, M., Kawahara, C., Ishioka, C., Kanamaru, R., Katoh, I., Ikawa, Y., Nimura, Y., Nakagawara, A., Obinata, M., Ikawa, S. Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nature Med. 4: 839-843, 1998. 3. Senoo, M., Seki, N., Ohira, M., Sugano, S., Watanabe, M., Inuzuka, S., Okamoto, T., Tachibana, M., Tanaka, T., Shinkai, Y., Kato, H. A second p53-related protein, p73L, with high homology to p73. Biochem. Biophys. Res. Commun. 248: 603-607, 1998. Note: Erratum: Biochem. Biophys. Res. Commun. 250: 536 only, 1998. 4. Trink, B., Okami, K., Wu, L., Sriuranpong, V., Jen, J., Sidransky, D. A new human p53 homologue. (Letter) Nature Med. 4: 747-748, 1998. 5. Yang, A., Kaghad, M., Wang, Y., Gillett, E., Fleming, M. D., Dotsch, V., Andrews, N. C., Caput, D., McKeon, F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Molec. Cell 2: 305-316, 1998. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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- 抗原
- p63 (TP63) (Tumor Protein P63 (TP63))
- 别名
- TP63 (TP63 产品)
- 背景
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Synonyms: Tumor protein 63,p63,Chronic ulcerative stomatitis protein,CUSP,Keratinocyte transcription factor KET,Transformation-related protein 63,TP63,Tumor protein p73-like,p73L,p40,p51,TP63,KET, P63, P73H, P73L, TP73L,
Tissue Specificity: Widely expressed, notably in heart, kidney, placenta, prostate, skeletal muscle, testis and thymus, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast, eye and prostate express high levels of DeltaN-type isoforms. Isoform 10 is predominantly expressed in skin squamous cell carcinomas, but not in normal skin tissues. .
Background: TP63 (Tumor Protein p63), also known as KET, is a protein that in humans is encoded by the TP63 gene. Yang et al. (1998) described the cloning of tumor protein p63, which shows strong homology to the tumor suppressor p53 and the p53-related protein p73. By fluorescence in situ hybridization, Yang et al. (1998) localized the human TP63 gene to chromosome 3q27-q29. Hibi et al. (2000) stated that p53 homologs known variously as p40, p51, p63, and p73L (Trink et al., 1998, Yang et al., 1998, Osada et al., 1998, Senoo et al., 1998) are isoforms of the same gene, which Hibi et al. (2000) referred to as AIS for amplified in squamous cell carcinoma.
Sequence Similarities: Belongs to the p53 family.
- 分子量
- 75 kDa
- UniProt
- Q9H3D4
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