PDK2 抗体 (C-Term)
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Quick Overview for PDK2 抗体 (C-Term) (ABIN3044044)
抗原
See all PDK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 379-392, C-Term
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原理
- Anti-PDK2 Antibody
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序列
- WRHYQTIQEA GDWC
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-PDK2 Antibody (ABIN3044044). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PDK2, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276) antibody
PDK2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 155-379) antibodyPDK2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 178-404) antibodyPDK2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3F2D7 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibodyPDK2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibodyPDK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 78-107), (N-Term) antibodyPDK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34663 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibodyPDK2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23089 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 378-407), (C-Term) antibodyPDK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03037 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibodyPDK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 7E5 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibodyPDK2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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别名
- PDK2
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背景
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Synonyms: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial,2.7.11.2,Pyruvate dehydrogenase kinase isoform 2,PDH kinase 2,PDKII,PDK2,PDHK2,
Tissue Specificity: Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung. .
Background: PDK2 (Pyruvate Dehydrogenase Kinase Isoenzyme 2), is an enzyme that in humans is encoded by the PDK2 gene. This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Sequence Similarities: Belongs to the PDK/BCKDK protein kinase family.
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分子量
- 46 kDa
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UniProt
- Q15119
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途径
- PI3K-Akt Signaling, RTK signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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