NADPH Oxidase 4 抗体 (C-Term)
(2 references)-
- 抗原 See all NADPH Oxidase 4 (NOX4) 抗体
- NADPH Oxidase 4 (NOX4)
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抗原表位
- AA 561-578, C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NADPH Oxidase 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 原理
- Anti-NADPH oxidase 4/NOX4 Antibody Picoband®
- 序列
- NRNNSYGTKF EYNKES
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-NADPH oxidase 4/NOX4 Antibody (ABIN3044011). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse NADPH oxidase 4, identical to the related rat sequence and different from the related human sequence by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NOX4 Primary Antibody
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anti-NADPH Oxidase 4 (NOX4) (AA 210-310) antibody
NOX4 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3H2G11 unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 328-578) antibodyNOX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 220-392) antibodyNOX4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 81-180) antibodyNOX4 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IP, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 210-424) antibodyNOX4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 124-153), (N-Term) antibodyNOX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34043 unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 124-153) antibodyNOX4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (C-Term) antibodyNOX4 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 201-300) antibodyNOX4 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 4 (NOX4) (AA 210-578) antibodyNOX4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Ago, T., Kitazono, T., Ooboshi, H., Iyama, T., Han, Y. H., Takada, J., Wakisaka, M., Ibayashi, S., Utsumi, H., Iida, M. Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase. Circulation 109: 227-233, 2004. 2. Geiszt, M., Kopp, J. B., Varnai, P., Leto, T. L. Identification of Renox, an NAD(P)H oxidase in kidney. Proc. Nat. Acad. Sci. 97: 8010-8014, 2000. 3. Shiose, A., Kuroda, J., Tsuruya, K., Hirai, M., Hirakata, H., Naito, S., Hattori, M., Sakaki Y., Sumimoto, H. A novel superoxide-producing NAD(P)H oxidase in kidney. J. Biol. Chem. 276: 1417-1423, 2001. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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: "A Cross Talk Between BRG1 and Males Absent on the First Contributes to Reactive Oxygen Species Production in a Mouse Model of Nonalcoholic Steatohepatitis." in: Antioxidants & redox signaling, (2018) (PubMed).
: "Obligatory role for GPER in cardiovascular aging and disease." in: Science signaling, Vol. 9, Issue 452, pp. ra105, (2017) (PubMed).
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: "A Cross Talk Between BRG1 and Males Absent on the First Contributes to Reactive Oxygen Species Production in a Mouse Model of Nonalcoholic Steatohepatitis." in: Antioxidants & redox signaling, (2018) (PubMed).
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- 抗原
- NADPH Oxidase 4 (NOX4)
- 别名
- NOX4 (NOX4 产品)
- 背景
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Synonyms: NADPH oxidase 4,1.6.3.-,Kidney oxidase-1,KOX-1,Kidney superoxide-producing NADPH oxidase,Renal NAD (P)H-oxidase,Superoxide-generating NADPH oxidase 4,Nox4,Renox,
Tissue Specificity: EXpressed in brain, in all layers of the cerebellum, in pyramidal cells of the Ammon horn and in Purkinje cells (at protein level). Expressed in osteoclasts, leukocytes, kidney, liver and lung. .
Background: NADPH oxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPH oxidases. This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Sequence Similarities: Contains 1 FAD-binding FR-type domain.
- 分子量
- 67 kDa
- 途径
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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