IGF2R 抗体 (C-Term)
(1 reference)Quick Overview for IGF2R 抗体 (C-Term) (ABIN3044000)
抗原
See all IGF2R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2475-2491, C-Term
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原理
- Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband®
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序列
- TKLVSFHDDS DEDLLHI
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody (ABIN3044000). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Mannose 6 Phosphate Receptor(Cation independent), different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody
IGF2R 适用: 人, Non-Human Primate WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-238 unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 424-529) antibodyIGF2R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2327-2491) antibodyIGF2R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibodyIGF2R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 160-311) antibodyIGF2R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F1G1 unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2441-2490) antibodyIGF2R 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (FITC)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 FITC
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (PE)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 PE
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (APC)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 APC
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2201-2400) antibodyIGF2R 适用: 人 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
1. Killian, J. K., Oka, Y., Jang, H.-S., Fu, X., Waterland, R. A., Sohda, T., Sakaguchi, S., Jirtle, R. L. Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations. Hum. Mutat. 18: 25-31, 2001. 2. Latos, P. A., Pauler, F. M., Koerner, M. V., Senergin, H. B., Hudson, Q. J., Stocsits, R. R., Allhoff, W., Stricker, S. H., Klement, R. M., Warczok, K. E., Aumayr, K., Pasierbek, P., Barlow, D. P. Airn transcriptional overlap, but not its IncRNA products, induces imprinted Igf2r silencing. Science 338: 1469-1472, 2012. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Insulin-like growth factors in endometrioid adenocarcinoma: correlation with clinico-pathological features and estrogen receptor expression." in: BMC cancer, Vol. 12, pp. 262, (2013) (PubMed).
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: "Insulin-like growth factors in endometrioid adenocarcinoma: correlation with clinico-pathological features and estrogen receptor expression." in: BMC cancer, Vol. 12, pp. 262, (2013) (PubMed).
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- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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别名
- IGF2R
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背景
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Synonyms: Cation-independent mannose-6-phosphate receptor,CI Man-6-P receptor,CI-MPR,M6PR,300 kDa mannose 6-phosphate receptor,MPR 300,Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor,IGF-II receptor,M6P/IGF2 receptor,M6P/IGF2R,CD222,IGF2R,MPRI,
Tissue Specificity: Highly expressed in liver, kidney, lung and skin. .
Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
Sequence Similarities: Belongs to the MRL1/IGF2R family.
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分子量
- 274 kDa
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UniProt
- P11717
抗原
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