CCR3 抗体 (N-Term)
Quick Overview for CCR3 抗体 (N-Term) (ABIN3043996)
抗原
See all CCR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-20, N-Term
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原理
- Anti-CCR3 Antibody Picoband®
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序列
- MTTSLDTVET FGTTSYYDDV
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CCR3 Antibody (ABIN3043996). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human CCR3.
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亚型
- IgG
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anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody
CCR3 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8E9H10 unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 251-355) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 306-355) antibodyCCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody (PE)CCR3 适用: 人 FACS 宿主: 小鼠 Monoclonal 5E8 PE
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 5-28) antibodyCCR3 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (N-Term) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (Extracellular Domain) antibodyCCR3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Blanchard, C., Wang, N., Stringer, K. F., Mishra, A., Fulkerson, P. C., Abonia, J. P., Jameson, S. C., Kirby, C., Konikoff, M. R., Collins, M. H., Cohen, M. B., Akers, R., Hogan, S. P., Assa'ad, A. H., Putnam, P. E., Aronow, B. J., Rothenberg, M. E. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116: 536-547, 2006. 2. Takeda, A., Baffi, J. Z., Kleinman, M. E., Cho, W. G., Nozaki, M., Yamada, K., Kaneko, H., Albuquerque, R. J. C., Dridi, S., Saito, K., Raisler, B. J., Budd, S. J., and 15 others. CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature 460: 225-230, 2009. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Thimerosal, 0.01 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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别名
- CCR3
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背景
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Synonyms: C-C chemokine receptor type 3,C-C CKR-3,CC-CKR-3,CCR-3,CCR3,CKR3,Eosinophil eotaxin receptor,CD193,CCR3,CMKBR3,
Tissue Specificity: In eosinophils as well as trace amounts in neutrophils and monocytes.
Background: C-C chemokine receptor type 3, also called CCR3 or CKR3 is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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分子量
- 200 kDa
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UniProt
- P51677
抗原
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