beta Arrestin 1 抗体 (N-Term)
Quick Overview for beta Arrestin 1 抗体 (N-Term) (ABIN3043990)
抗原
See all beta Arrestin 1 (ARRB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 82-103, N-Term
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原理
- Anti-beta Arrestin 1/ARRB1 Antibody Picoband®
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序列
- ANVQSFPPAP EDKKPLTRLQ ER
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-beta Arrestin 1/ARRB1 Antibody (ABIN3043990). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human beta Arrestin 1, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Arrestin, beta 1 (ARRB1) (AA 3-246) antibody
ARRB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 169-418) antibodyARRB1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, ICC, FACS 宿主: 兔 Monoclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 336-363), (C-Term) antibodyARRB1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB31615 unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 1-260) antibodyARRB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 369-418) antibodyARRB1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 343-371), (C-Term) antibodyARRB1 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (Ser157) antibodyARRB1 适用: 人, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Buchanan, F. G., Gorden, D. L., Matta, P., Shi, Q., Matrisian, L. M., DuBois, R. N. Role of beta-arrestin 1 in the metastatic progression of colorectal cancer. Proc. Nat. Acad. Sci. 103: 1492-1497, 2006. 2. Nelson, C. D., Perry, S. J., Regier, D. S., Prescott, S. M., Topham, M. K., Lefkowitz, R. J.Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins. Science 315: 663-666, 2007. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
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别名
- ARRB1
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背景
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Synonyms: Beta-arrestin-1;Arrestin beta-1;ARRB1;ARR1;
Background: Arrestin, beta 1, also known as ARRB1, is a protein which in humans is encoded by the ARRB1 gene. Members of arrestin/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. By fluorescence in situ hybridization, this gene is mapped to 11q13.4. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.
Sequence Similarities: Belongs to the arrestin family.
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分子量
- 18 kDa
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UniProt
- P49407
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途径
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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