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Gelsolin 抗体 (C-Term)

Name: Gelsolin 抗体 (C-Term)
SKU: ABIN3043978
Availability: OutOfStock

Cited in 1 publication. This 兔多克隆 anti-Gelsolin antibody specifically detects Gelsolin in WB, IHC, ICC, FACS 和 IF. The antibody is reactive with 人, 小鼠, 大鼠和猴 samples.

Western Blotting (WB) image for anti-Gelsolin (GSN) (AA 763-775), (C-Term) antibody (ABIN3043978) (Gelsolin 抗体 (C-Term))

Anti-Gelsolin antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue (Gelsolin 抗体 (C-Term))

IHC

Anti-Gelsolin antibody, IHC(P) IHC(P): Human Lung Cancer Tissue (Gelsolin 抗体 (C-Term))

IHC

Anti-Gelsolin antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue (Gelsolin 抗体 (C-Term))

IHC

Anti-Gelsolin antibody, ICC ICC: NIH3T3 Cell (Gelsolin 抗体 (C-Term))

IHC

5 images

(1 reference)

产品编号 ABIN3043978

发货至: 中国

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Quick Overview for Gelsolin 抗体 (C-Term) (ABIN3043978)

抗原

See all Gelsolin (GSN) 抗体

Gelsolin (GSN)

适用

人, 小鼠, 大鼠, 猴

宿主

兔

克隆类型

多克隆

标记

This Gelsolin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Discover our top product GSN Primary Antibody

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AA 763-775, C-Term

原理

Anti-Gelsolin/GSN Antibody

序列

WDDDYWSVDP LDR

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Gelsolin/GSN Antibody (ABIN3043978). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Gelsolin, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.

亚型

IgG
anti-Gelsolin (GSN) (AA 170-423) antibody
GSN 适用: Cow WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

anti-Gelsolin (GSN) (AA 577-771) antibody
GSN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gelsolin (GSN) (AA 674-782) antibody
GSN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gelsolin (GSN) (AA 543-782) antibody
GSN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Gelsolin (GSN) (AA 673-782) antibody
GSN 适用: 人 WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G5 unconjugated

anti-Gelsolin (GSN) antibody
GSN 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5E3B9 unconjugated

anti-Gelsolin (GSN) (AA 432-553) antibody
GSN 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Gelsolin (GSN) (AA 432-625) antibody
GSN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gelsolin (GSN) (AA 1-782) antibody
GSN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Gelsolin (GSN) (C-Term) antibody
KO Validated GSN 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Monkey, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunocytochemistry , 0.5-1 μg/mL, Mouse
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Guo, Cui, Jiang, Zhang, Jiang: "Proteomics of acute heart failure in a rat post-myocardial infarction model." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1946-1956, (2018) (PubMed).
抗原

Gelsolin (GSN)

别名

GSN

背景

Synonyms: Gelsolin,AGEL,Actin-depolymerizing factor,ADF,Brevin,GSN,
Tissue Specificity: Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells.
Background: Gelsolin also known as GNS is an actin-binding protein that is a key regulator of actin filament assembly and disassembly. Gelsolin is one of the most potent members of the actin-severing gelsolin/villin superfamily. The gene was assigned to human chromosome 9q33.2. Gelsolin is also known as brevin, or actin-depolymerizing factor, it is the principal intracellular and extracellular actin-severing protein. Gelsolin and Gc protein together constitute the extracellular actin-scavenger system which prevents the toxic effects of actin release into the extracellular space under circumstances of cell necrosis. Gelsolin may have therapeutic potential as a mucolytic agent in CF patients. The antiapoptotic activity of gelsolin seems to prevent a step leading to cytochrome c release from the mitochondria into the cytosol.
Sequence Similarities: Belongs to the villin/gelsolin family.

分子量

90 kDa

UniProt

P06396

途径

Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy