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MSH2 抗体 (AA 337-583)

MSH2 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

Anti- MSH2 Picoband antibody, Western blotting All lanes: Anti MSH2 at 0. (MSH2 抗体 (AA 337-583))

Anti- MSH2 Picoband antibody,ICC ICC: SMMC Cell (MSH2 抗体 (AA 337-583))

Anti- MSH2 Picoband antibody, IHC(P) IHC(P): Mouse Intestine Tissue (MSH2 抗体 (AA 337-583))

Anti- MSH2 Picoband antibody, IHC(P) IHC(P): Rat Intestine Tissue (MSH2 抗体 (AA 337-583))

Anti- MSH2 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue (MSH2 抗体 (AA 337-583))

5 images

(1 reference)

产品编号 ABIN3043885

发货至: 中国

Datasheet as PDF

抗原 See all MSH2 抗体

MSH2 (Mismatch Repair Protein 2 (MSH2))
抗原表位
15

8

7

6

5

4

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 337-583
适用
79

38

19

6

6

4

4

3

3

3

3

2

2

1

1

1
人, 小鼠, 大鼠
宿主
73

20

1
兔
Compatible Secondaries
克隆类型
69

25

1
多克隆
标记
63

4

4

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MSH2 antibody is un-conjugated
应用范围
55

38

25

25

18

13

13

10

9

9

7

4

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

原理

Rabbit IgG polyclonal antibody for DNA mismatch repair protein Msh2(MSH2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for DNA mismatch repair protein Msh2(MSH2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: mutS homolog 2
Protein Name: DNA mismatch repair protein Msh2

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human MSH2 recombinant protein (Position: Q337-N583). Human MSH2 shares 94% and 93% amino acid (aa) sequence identity with mouse and rat MSH2, respectively.

亚型

IgG

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anti-Mismatch Repair Protein 2 (MSH2) (AA 1-300) antibody
MSH2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 442-586) antibody
MSH2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2E2C7 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 1-934) antibody
MSH2 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 835-934) antibody
MSH2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4B2 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 224-313) antibody
MSH2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SYP-3551 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 442-586) antibody
MSH2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F10D6 unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 637-665) antibody
MSH2 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 2-254) antibody
MSH2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Mismatch Repair Protein 2 (MSH2) (AA 1-934) antibody
MSH2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for MSH2 is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Zhang, Yue, Wang, Li, Xin, Pang, Zheng, Xie: "Cisplatin upregulates MSH2 expression by reducing miR-21 to inhibit A549 cell growth." in: Biomedicine & pharmacotherapy, Vol. 67, Issue 2, pp. 97-102, (2014) (PubMed).
抗原

MSH2 (Mismatch Repair Protein 2 (MSH2))

别名

MSH2 (MSH2 产品)

背景

DNA mismatch repair protein Msh2, also known as MutS protein homolog 2 or MSH2, is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2. MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein, MSH2 which forms aheterodimer with MSH6 to make the human MutSα mismatch repair complex. It also dimerizes with MSH3 to form the MutSβ DNA repair complex. MSH2 is involved in many different forms of DNA repair, including transcription-coupled repair, homologous recombination, and base excision repair. It has been found that MSH2 may also be a coactivator of ESR1-dependent gene expression.

Synonyms: BAT26 antibody|COCA 1 antibody|COCA1 antibody|DNA mismatch repair protein Msh2 antibody|FCC 1 antibody|FCC1 antibody|hMSH2 antibody|HNPCC 1 antibody|HNPCC antibody|HNPCC1 antibody|LCFS2 antibody|MSH 2 antibody|Msh2 antibody|MSH2_HUMAN antibody|MutS homolog 2 antibody|MutS homolog 2 colon cancer nonpolyposis type 1 antibody|MutS protein homolog 2 antibody

基因ID

4436

UniProt

P43246

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response

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