JUP 抗体 (AA 556-745)
Quick Overview for JUP 抗体 (AA 556-745) (ABIN3043864)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 556-745
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原理
- Anti-gamma Catenin/JUP Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-gamma Catenin/JUP Antibody Picoband® (ABIN3043864). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human gamma Catenin recombinant protein (Position: M556-A745). Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin.
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亚型
- IgG
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anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-745) antibodyJUP 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyVerified JUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal CTNG-1664 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat WB, IF, FACS 宿主: 小鼠 Monoclonal 15F11 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 1-10E05 unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-300) antibodyJUP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Kolligs, F. T., Kolligs, B., Hajra, K. M., Hu, G., Tani, M., Cho, K. R., Fearon, E. R. : Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev. 14: 1319-1331, 2000. 2. "Entrez Gene: JUP junction plakoglobin" -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- JUP (Junction Plakoglobin (JUP))
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别名
- JUP
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背景
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Synonyms: Junction plakoglobin;Catenin gamma;Desmoplakin III;Desmoplakin-3;JUP;CTNNG, DP3;
Tissue Specificity: Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. .
Background: Junction plakoglobin (JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to β-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
Sequence Similarities: Belongs to the beta-catenin family.
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分子量
- 82 kDa
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基因ID
- 3728
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UniProt
- P14923
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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