FMO3 抗体 (C-Term)
Quick Overview for FMO3 抗体 (C-Term) (ABIN3043830)
抗原
See all FMO3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 404-433, C-Term
-
原理
- Anti-FMO3 Antibody Picoband®
-
序列
- DMMNDINEKM EKKRKWFGKS ETIQTDYIVY
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-FMO3 Antibody Picoband® (ABIN3043830). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human FMO3, different from the related mouse sequence by eight amino acids, and from the related rat sequence by six amino acids.
-
亚型
- IgG
-
-
anti-Flavin Containing Monooxygenase 3 (FMO3) antibody
FMO3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 1-532) antibodyFMO3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) antibodyFMO3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 81-130) antibodyFMO3 适用: 人, 大鼠, Cow, 犬, 马, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 1-532) antibodyFMO3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (N-Term) antibodyFMO3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 263-532) antibodyFMO3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (AA 30-56), (N-Term) antibodyFMO3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21188 unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) (N-Term) antibodyFMO3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Flavin Containing Monooxygenase 3 (FMO3) antibodyFMO3 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Akerman, B. R., Chow, L., Forrest, S., Youil, R., Cashman, J., Treacy, E. P. Mutations in the flavin-containing monoxygenase (sic) form 3 (FMO3) gene cause trimethylaminuria, fish odour syndrome. (Abstract) Am. J. Hum. Genet. 61 (suppl.): A53 only, 1997. 2. Cashman, J. R., Zhang, J. Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation. Drug Metab. Dispos. 30: 1043-1052, 2002. 3. Dolphin, C. T., Janmohamed, A., Smith, R. L., Shephard, E. A., Phillips, I. R. Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome. Nature Genet. 17: 491-494, 1997. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- FMO3 (Flavin Containing Monooxygenase 3 (FMO3))
-
别名
- FMO3
-
背景
-
Synonyms: Dimethylaniline monooxygenase [N-oxide-forming] 3,1.14.13.8,Dimethylaniline oxidase 3,FMO II,FMO form 2,Hepatic flavin-containing monooxygenase 3,FMO 3,Trimethylamine monooxygenase,1.14.13.148,FMO3,
Tissue Specificity: Liver.
Background: FMO3 (Flavin-containing Monooxygenase 3) is an enzyme that in humans is encoded by the FMO3 gene. The mammalian flavin-containing monooxygenases (FMO) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. The FMO3 gene contains 1 noncoding and 8 coding exons. And the FMO3 gene is mapped on 1q24.3. Using quantitative RNase protection assays, FMO3 is present in low abundance in fetal liver and lung and in adult kidney and lung, and in much greater abundance in adult liver. By Western blot analysis of human liver microsomal samples ranging from 8 weeks gestation to 18 years of age, FMO1 is the major fetal isoform and FMO3 is the major adult isoform. FMO3 was expressed at intermediate levels until 11 years of age when a gender-independent increase in FMO3 expression was observed during puberty. Sufferers of trimethylaminuria may display a reduced ability to metabolize substrates for FMO3 such as nicotine. FMO3 metabolizes a number of drugs, including amphetamine, clozapine, deprenyl, metamphetamine, tamoxifen, ethionamide, thiacetazone, and sulindac sulfide.
Sequence Similarities: Belongs to the FMO family.
-
分子量
- 60 kDa
-
基因ID
- 2328
-
UniProt
- P31513
抗原
-
