CEBPB 抗体 (AA 1-200)
Quick Overview for CEBPB 抗体 (AA 1-200) (ABIN3043809)
抗原
See all CEBPB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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原理
- Anti-CEBP Beta/CEBPB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CEBP Beta/CEBPB Antibody Picoband® (ABIN3043809). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CEBP Beta recombinant protein (Position: M1-A200). Human CEBP Beta shares 61% amino acid (aa) sequence identity with both mouse and rat CEBP Beta.
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亚型
- IgG
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anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (N-Term) antibody
KO Validated CEBPB 适用: 人 WB, IHC, IP, IHC (p), IF, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (pThr235) antibodyCEBPB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (Internal Region) antibodyCEBPB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 150-250) antibodyCEBPB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) antibodyCEBPB 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3H9 unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 271-298) antibodyCEBPB 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 68-81) antibodyVerified CEBPB 适用: 人, 小鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 271-298), (C-Term) antibodyCEBPB 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20651 unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (pSer235) antibodyCEBPB 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 201-250), (pThr235) antibodyCEBPB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
1. Szpirer C, Riviere M, Cortese R, Nakamura T, Islam MQ, Levan G, Szpirer J (Jul 1992). "Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HGF)". Genomics 13 (2): 293-300. 2. Cao Z, Umek RM, McKnight SL (Oct 1991). "Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells". Genes Dev 5 (9): 1538-52. 3. Harries LW, Pilling LC, Hernandez LD, Bradley-Smith R, Henley W, Singleton AB, Guralnik JM, Bandinelli S, Ferrucci L, Melzer D (2012). -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
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别名
- CEBPB
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背景
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Synonyms: CCAAT/enhancer-binding protein beta ,C/EBP beta ,Liver activator protein,LAP,Liver-enriched inhibitory protein,LIP,Nuclear factor NF-IL6,Transcription factor 5,TCF-5,CEBPB ,TCF5,PP9092,
Tissue Specificity: Expressed at low levels in the lung, kidney and spleen.
Background: CCAAT/enhancer-binding protein beta, also known as is CEBP-beta, is a protein that in humans is encoded by the CEBPB gene. It mapped to 20q13.13. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. CEBP-beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of CEBP-beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.
Sequence Similarities: Belongs to the bZIP family. C/EBP subfamily.
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分子量
- 46 kDa
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基因ID
- 1051
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UniProt
- P17676
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途径
- Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation
抗原
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