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CEBPB 抗体 (AA 1-200)

This 兔 多克隆 anti-CEBPB antibody specifically detects CEBPB in WB, IHC, IF, FACS 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN3043809
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for CEBPB 抗体 (AA 1-200) (ABIN3043809)

抗原

See all CEBPB 抗体
CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

适用

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宿主

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克隆类型

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多克隆

标记

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This CEBPB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
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    AA 1-200

    原理

    Anti-CEBP Beta/CEBPB Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-CEBP Beta/CEBPB Antibody (ABIN3043809). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CEBP Beta recombinant protein (Position: M1-A200). Human CEBP Beta shares 61% amino acid (aa) sequence identity with both mouse and rat CEBP Beta.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

    别名

    CEBPB

    背景

    Synonyms: CCAAT/enhancer-binding protein beta ,C/EBP beta ,Liver activator protein,LAP,Liver-enriched inhibitory protein,LIP,Nuclear factor NF-IL6,Transcription factor 5,TCF-5,CEBPB ,TCF5,PP9092,

    Tissue Specificity: Expressed at low levels in the lung, kidney and spleen.

    Background: CCAAT/enhancer-binding protein beta, also known as is CEBP-beta, is a protein that in humans is encoded by the CEBPB gene. It mapped to 20q13.13. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. CEBP-beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of CEBP-beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.

    Sequence Similarities: Belongs to the bZIP family. C/EBP subfamily.

    分子量

    46 kDa

    基因ID

    1051

    UniProt

    P17676

    途径

    Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation
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