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p63 抗体 (AA 311-680)

TP63 适用: 人 WB, ICC, IF, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043716
发货至: 中国
  • 抗原 See all p63 (TP63) 抗体
    p63 (TP63) (Tumor Protein P63 (TP63))
    抗原表位
    • 12
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 311-680
    适用
    • 63
    • 24
    • 22
    • 4
    • 2
    • 2
    宿主
    • 48
    • 19
    • 1
    克隆类型
    • 42
    • 26
    多克隆
    标记
    • 53
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This p63 antibody is un-conjugated
    应用范围
    • 41
    • 30
    • 20
    • 12
    • 10
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    原理
    Rabbit IgG polyclonal antibody for Tumor protein 63(TP63) detection. Tested with WB, IHC-P, ICC in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Tumor protein 63(TP63) detection. Tested with WB, IHC-P, ICC in Human.
    Gene Name: tumor protein p63
    Protein Name: Tumor protein 63
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human p63 recombinant protein (Position: S311-E680). Human p63 shares 98% amino acid (aa) sequence identity with both mouse and rat p63.
    亚型
    IgG
    Top Product
    Discover our top product TP63 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for p63 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    p63 (TP63) (Tumor Protein P63 (TP63))
    别名
    TP63 (TP63 产品)
    别名
    AIS antibody, B(p51A) antibody, B(p51B) antibody, EEC3 antibody, KET antibody, LMS antibody, NBP antibody, OFC8 antibody, RHS antibody, SHFM4 antibody, TP53CP antibody, TP53L antibody, TP73L antibody, p40 antibody, p51 antibody, p53CP antibody, p63 antibody, p73H antibody, p73L antibody, TP63 antibody, tp63 antibody, DNp63 antibody, id:ibd3516 antibody, tp73l antibody, wu:fc89f04 antibody, wu:fk85h07 antibody, wu:fk88b02 antibody, Ket antibody, P73l antibody, Tp73l antibody, Trp63 antibody, TRP63 antibody, AI462811 antibody, P51/P63 antibody, P63 antibody, Tp63 antibody, Trp53rp1 antibody, Xp63 antibody, ket antibody, np63 antibody, tp73l-A antibody, trp63 antibody, tumor protein p63 antibody, transformation related protein 63 antibody, tumor protein p63 L homeolog antibody, TP63 antibody, tp63 antibody, Tp63 antibody, Trp63 antibody, tp63.L antibody
    背景
    Tumor protein p63 (TP63), also known as the p63 or TP73L is a protein that in humans is encoded by the TP63 gene. It is mapped to 3q28. TP63 is a member of the p53 family of transcription factors. This gene encodes for two main isoforms by alternative promoters (TAp63 and ΔNp63). TP63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity. It has been found that the combined loss of TP63 and p73 results in the failure of cells containing functional p53 to undergo apoptosis in response to DNA damage. TP63 is an essential regulator of stem cell maintenance in stratified epithelial tissues. Tp63 is also critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis.

    Synonyms: AIS antibody|Amplified in squamous cell carcinoma antibody|B(p51A) antibody|B(p51B) antibody|Chronic ulcerative stomatitis protein antibody|CUSP antibody|DN p63 alpha 1 antibody|DNp63 antibody|EEC3 antibody|Keratinocyte transcription factor antibody|Keratinocyte transcription factor KET antibody|KET antibody|LMS antibody|MGC115972 antibody|MGC192897 antibody|NBP antibody|OFC8 antibody|OTTHUMP00000209732 antibody|OTTHUMP00000209733 antibody|OTTHUMP00000209734 antibody|OTTHUMP00000209735 antibody|OTTHUMP00000209737 antibody|OTTHUMP00000209738 antibody|OTTHUMP00000209739 antibody|OTTHUMP00000209740 antibody|OTTHUMP00000209741 antibody|OTTHUMP00000209742 antibody|OTTHUMP00000209743 antibody|OTTHUMP00000209744 antibody|p40 antibody|p51 antibody|P51/P63 antibody|p53 like transcription factor antibody|p53 related protein antibody|p53-related protein p63 antibody|p53CP antibody|p63 antibody|P63_HUMAN antibody|P73 antibody|p73H antibody|p73L antibody|RHS antibody|SHFM4 antibody|TAp63alpha antibody|TP53CP antibody|TP53L antibody|TP63 antibody|TP73 antibody|TP73L antibody|Transformation related protein 63 antibody|Transformation-related protein 63 antibody|Trp53rp1 antibody|Trp63 antibody|Tumor protein 63 antibody|tumor protein 63 kDa with strong homology to p53 antibody|Tumor protein p53-competing protein antibody|Tumor protein p53-like antibody|tumor protein p63 antibody|Tumor protein p63 deltaN isoform delta antibody|Tumor protein p73 antibody|tumor protein p73-like antibody
    基因ID
    8626
    UniProt
    Q9H3D4
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