MAPK6 抗体 (AA 520-721)
Quick Overview for MAPK6 抗体 (AA 520-721) (ABIN3043611)
抗原
See all MAPK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 520-721
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原理
- Anti-MAPK6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MAPK6 Antibody Picoband® (ABIN3043611). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MAPK6 recombinant protein (Position: E520-N721). Human MAPK6 shares 86.2% and 82.8% amino acid (aa) sequence identity with mouse and rat MAPK6, respectively.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 612-721) antibody
MAPK6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 612-721) antibodyMAPK6 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibodyMAPK6 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 1-316) antibodyMAPK6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibodyMAPK6 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (pSer189) antibodyMAPK6 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB5800 unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 372-721) antibodyKO Validated MAPK6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (Center) antibodyMAPK6 适用: 人, 小鼠, Cow, 小鸡, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 21-120) antibodyMAPK6 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 383-712) antibodyMAPK6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: MAPK6 mitogen-activated protein kinase 6". 2. Cheng M, Boulton TG, Cobb MH (1996). "ERK3 is a constitutively nuclear protein kinase". J. Biol. Chem.271 (15): 8951-8958. 3. Meloche S, Beatty BG, Pellerin J (Dec 1996). "Primary structure, expression and chromosomal locus of a human homolog of rat ERK3". Oncogene 13 (7): 1575-9. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
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别名
- MAPK6
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背景
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Synonyms: Mitogen-activated protein kinase 6,MAP kinase 6,MAPK 6,2.7.11.24,Extracellular signal-regulated kinase 3,ERK-3,MAP kinase isoform p97,p97-MAPK,MAPK6,ERK3, PRKM6,
Tissue Specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
Background: Mitogen-activated protein kinase 6 is an enzyme that in humans is encoded by the MAPK6 gene. It is mapped to 15q21. The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblastsupon treatment with serum or phorbol esters.
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分子量
- 100 kDa
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基因ID
- 5597
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UniProt
- Q16659
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
抗原
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