MAPK13 抗体 (C-Term)
Quick Overview for MAPK13 抗体 (C-Term) (ABIN3043610)
抗原
See all MAPK13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 332-365, C-Term
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原理
- Anti-SAPK4/MAPK13 Antibody Picoband®
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序列
- KLTVDEWKQH IYKEIVNFSP IARKDSRRRS GMKL
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SAPK4/MAPK13 Antibody Picoband® (ABIN3043610). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human SAPK4 , different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 251-365) antibody
MAPK13 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 1-365) antibodyMAPK13 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C10-1C7 unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 251-365) antibodyMAPK13 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 1-365) antibodyMAPK13 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 1-365) antibodyMAPK13 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 251-365) antibodyMAPK13 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) antibodyMAPK13 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 12B2 unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) antibodyMAPK13 适用: 人, 小鼠, 大鼠, 猴, 犬 WB, IF 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 1-365) antibodyMAPK13 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 335-365), (C-Term) antibodyMAPK13 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal RB0912 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Goedert, M., Cuenda, A., Craxton, M., Jakes, R., Cohen, P. Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6), comparison of its substrate specificity with that of other SAP kinases. EMBO J. 16: 3563-3571, 1997. 2. Kumar, S., McDonnell, P. C., Gum, R. J., Hand, A. T., Lee, J. C., Young, P. R. Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem. Biophys. Res. Commun. 235: 533-538, 1997. 3. Wang, X. S., Diener, K., Manthey, C. L., Wang, S., Rosenzweig, B., Bray, J., Delaney, J., Cole, C. N., Chan-Hui, P.-Y., Mantlo, N., Lichenstein, H. S., Zukowski, M., Yao, Z. Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase. J. Biol. Chem. 272: 23668-23674, 1997. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))
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别名
- MAPK13
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背景
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Synonyms: Mitogen-activated protein kinase 13,MAP kinase 13,MAPK 13,2.7.11.24,Mitogen-activated protein kinase p38 delta,MAP kinase p38 delta,Stress-activated protein kinase 4,MAPK13,PRKM13, SAPK4,
Tissue Specificity: Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells. .
Background: MAPK13 (Mitogen-Activated Protein Kinase 13), also called p38-DELTA or Stress-Activated Protein Kinase 4 (SAPK4), is an enzyme that in humans is encoded by the MAPK13 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
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分子量
- 42 kDa
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基因ID
- 5603
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UniProt
- O15264
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Hepatitis C, BCR Signaling, S100 Proteins
抗原
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