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MAPK13 抗体 (AA 1-365)

MAPK13 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7159988
发货至: 中国
  • 抗原 See all MAPK13 抗体
    MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-365
    适用
    • 73
    • 27
    • 25
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
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    宿主
    • 58
    • 12
    • 3
    克隆类型
    • 59
    • 14
    多克隆
    标记
    • 32
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This MAPK13 antibody is un-conjugated
    应用范围
    • 44
    • 31
    • 13
    • 13
    • 10
    • 8
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Mitogen-activated protein kinase 13 protein (1-365AA)
    亚型
    IgG
    Top Product
    Discover our top product MAPK13 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MAPK13 (Mitogen-Activated Protein Kinase 13 (MAPK13))
    别名
    MAPK13 (MAPK13 产品)
    别名
    F24B9.3 antibody, F24B9_3 antibody, MAPK 13 antibody, MAPK-13 antibody, PRKM13 antibody, SAPK4 antibody, p38delta antibody, Serk4 antibody, Prkm13 antibody, sapk4 antibody, prkm13 antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 13 antibody, mitogen activated protein kinase 13 antibody, ATMPK13 antibody, MAPK13 antibody, Mapk13 antibody, mapk13 antibody
    背景

    Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K. Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. Mediates UV irradiation induced up-regulation of the gene expression of CXCL14. Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development. Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway. MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells.

    Aliases: MAP kinase 13 antibody, MAP kinase p38 delta antibody, MAPK 13 antibody, MAPK-13 antibody, Mapk13 antibody, MGC99536 antibody, Mitogen activated protein kinase 13 antibody, Mitogen-activated protein kinase 13 antibody, Mitogen-activated protein kinase p38 delta antibody, MK13_HUMAN antibody, OTTHUMP00000016282 antibody, OTTHUMP00000016283 antibody, p38 delta antibody, P38delta antibody, PRKM13 antibody, SAPK 4 antibody, SAPK4 antibody, Stress activated protein kinase 4 antibody, Stress-activated protein kinase 4 antibody

    UniProt
    O15264
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Hepatitis C, BCR Signaling, S100 Proteins
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