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FAK 抗体 (C-Term)

Name: FAK 抗体 (C-Term)
SKU: ABIN3043556
Availability: OutOfStock

There are 2+ publications for this product available. The 兔多克隆 anti-FAK antibody is suitable to detect FAK in samples from 人, 小鼠和大鼠. It has been validated for WB 和 IHC.

Western Blotting (WB) image for anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (C-Term) antibody (ABIN3043556) (FAK 抗体 (C-Term))

IHC analysis of FAK/PTK2 using anti-FAK/PTK2 antibody (ABIN3043556). (FAK 抗体 (C-Term))

IHC

Western blot analysis of FAK/PTK2 using anti-FAK/PTK2 antibody (ABIN3043556). (FAK 抗体 (C-Term))

3 images

(2 references)

产品编号 ABIN3043556

发货至: 中国

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Quick Overview for FAK 抗体 (C-Term) (ABIN3043556)

抗原

See all FAK (PTK2) 抗体

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This FAK antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product PTK2 Primary Antibody

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C-Term

原理

Anti-FAK/PTK2 Antibody

序列

AHALAVDAKN LLDVIDQARL KMLGQTRPH

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

identical to the related mouse,rat sequences.

产品特性

Anti-FAK/PTK2 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human PTK2, identical to the related mouse and rat sequences.

亚型

IgG
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr397) antibody
PTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 700-800) antibody
PTK2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 798-1041) antibody
PTK2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 355-490) antibody
PTK2 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 2C3 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr576) antibody
PTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 396-423) antibody
PTK2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20775 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 821-848), (C-Term) antibody
PTK2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20776 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 1-680) antibody
PTK2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr861) antibody
PTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 10H7E9 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Su, Zhang, Mao, Liu, Zheng, Zhang, Su: "Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer." in: Oncology letters, Vol. 9, Issue 2, pp. 595-603, (2015) (PubMed).

Cao, Xing, Yang, Mei: "Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis." in: Experimental and therapeutic medicine, Vol. 7, Issue 1, pp. 280-286, (2013) (PubMed).
抗原

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

别名

PTK2

背景

Background: PTK2 protein tyrosine kinase 2 (PTK2), also known as Focal Adhesion Kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene. This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Gene Full Name: protein tyrosine kinase 2

分子量

125 kDa

基因ID

5747

UniProt

Q05397

途径

Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling