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ABI1 抗体 (N-Term)

Name: ABI1 抗体 (N-Term)
SKU: ABIN3043515
Availability: OutOfStock

ABI1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Abl-Interactor 1 (ABI1) (AA 151-175), (N-Term) antibody (ABIN3043515) (ABI1 抗体 (N-Term))

Anti- SSH3BP1 Picoband antibody, IHC(P) IHC(P): Rat Brain Tissue (ABI1 抗体 (N-Term))

IHC

Anti- SSH3BP1 Picoband antibody, IHC(P) IHC(P): Mouse Brain Tissue (ABI1 抗体 (N-Term))

IHC

IHC analysis of SSH3BP1 using anti-SSH3BP1 antibody . (ABI1 抗体 (N-Term))

IHC

4 images

(1 reference)

产品编号 ABIN3043515

发货至: 中国

Datasheet as PDF

抗原 See all ABI1 抗体

ABI1 (Abl-Interactor 1 (ABI1))
抗原表位
14

11

8

4

4

2

2

2

1

1
AA 151-175, N-Term
适用
44

38

28

6

6

5

4

4

4

3

3

1

1

1

1

1
人, 大鼠, 小鼠
宿主
60
兔
Compatible Secondaries
克隆类型
60
多克隆
标记
31

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ABI1 antibody is un-conjugated
应用范围
42

15

12

12

12

11

11

6

6

4

4

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

原理

Anti-SSH3BP1/ABI1 Antibody Picoband®

序列

HGVKWLKAKH GNNQPARTGT LSRTN

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-SSH3BP1/ABI1 Antibody Picoband® (ABIN3043515). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human ABI1, identical to the related mouse and rat sequences.

亚型

IgG

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Discover our top product ABI1 Primary Antibody
anti-Abl-Interactor 1 (ABI1) (AA 1-182) antibody
ABI1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) (AA 180-230) antibody
ABI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) antibody
ABI1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) (AA 483-494), (C-Term) antibody
ABI1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) (AA 81-108), (N-Term) antibody
ABI1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22014 unconjugated

anti-Abl-Interactor 1 (ABI1) antibody
ABI1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) (AA 81-108) antibody
ABI1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) (C-Term) antibody
ABI1 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) (AA 101-200) antibody
ABI1 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Abl-Interactor 1 (ABI1) (AA 325-375) antibody
ABI1 适用: 人, 小鼠 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Tani, K., Sato, S., Sukezane, T., Kojima, H., Hirose, H., Hanafusa, H., Shishido, T. : Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian Enabled (Mena) by c-Abl kinase. J. Biol. Chem. 278: 21685-21692, 2003. 2. Taki, T., Shibuya, N., Taniwaki, M., Hanada, R., Morishita, K., Bessho, F., Yanagisawa, M., Hayashi, Y. : ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10,11)(p11.2,q23). Blood 92: 1125-1130, 1998.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Cui, Yu, Dong, Chen, Zhang, Liu: "Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma." in: Medical oncology (Northwood, London, England), Vol. 27, Issue 3, pp. 632-9, (2010) (PubMed).
抗原

ABI1 (Abl-Interactor 1 (ABI1))

别名

ABI1 (ABI1 产品)

背景

Synonyms: Abl interactor 1,Abelson interactor 1,Abi-1,Abl-binding protein 4,AblBP4,Eps8 SH3 domain-binding protein,Eps8-binding protein,Nap1-binding protein,Nap1BP,Spectrin SH3 domain-binding protein 1,e3B1,ABI1,SSH3BP1,
Tissue Specificity: Widely expressed, with highest expression in brain. .
Background: SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.
Sequence Similarities: Belongs to the ABI family.

分子量

65 kDa

基因ID

10006

途径

RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling