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BIRC7 抗体 (AA 87-298)

BIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043512
发货至: 中国
  • 抗原 See all BIRC7 抗体
    BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
    抗原表位
    • 14
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 87-298
    适用
    • 58
    • 15
    • 14
    • 1
    • 1
    • 1
    • 1
    宿主
    • 53
    • 6
    克隆类型
    • 53
    • 6
    多克隆
    标记
    • 30
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIRC7 antibody is un-conjugated
    应用范围
    • 46
    • 19
    • 17
    • 12
    • 12
    • 12
    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Anti-Livin/BIRC7 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-Livin/BIRC7 Antibody (ABIN3043512). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived human Livin recombinant protein (Position: E87-S298). Human Livin shares 69.8% amino acid (aa) sequence identity with mouse Livin.
    亚型
    IgG
    Top Product
    Discover our top product BIRC7 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, -
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: BIRC7 baculoviral IAP repeat-containing 7 (livin)". 2. Kasof GM, Gomes BC (May 2001). "Livin, a novel inhibitor of apoptosis protein family member". J Biol Chem 276 (5): 3238-46. 3. Lin JH, Deng G, Huang Q, Morser J (Feb 2001). "KIAP, a novel member of the inhibitor of apoptosis protein family". Biochem Biophys Res Commun 279 (3): 820-31.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Guo, Gao, Zhang, Jing, Liu, Shi, Zhai, Jing, Du: "Expression and clinical significance of livin protein in hepatocellular carcinoma." in: Disease markers, Vol. 35, Issue 5, pp. 489-96, (2014) (PubMed).

  • 抗原
    BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
    别名
    BIRC7 (BIRC7 产品)
    背景

    Synonyms: Baculoviral IAP repeat-containing protein 7,6.3.2.-,Kidney inhibitor of apoptosis protein,KIAP,Livin,Melanoma inhibitor of apoptosis protein,ML-IAP,RING finger protein 50,Baculoviral IAP repeat-containing protein 7 30 kDa subunit,Truncated livin,p30-Livin,tLivin,BIRC7,KIAP, LIVIN, MLIAP, RNF50,UNQ5800/PRO19607/PRO21344,

    Tissue Specificity: Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.

    Background: Baculoviral IAP repeat-containing protein 7 is a protein that in humans is encoded by the BIRC7 gene. This protein is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) and a RING finger motif. Its gene is mapped to 20q13.3. It has got 280- and 298- amino acids. The protein is highly expressed in melanomas while lowly expressed in some lymphomas, fetal kidney, fetal liver, testis and thymus. BIRC7 plays a vital role in blocking apoptosis induced.

    Sequence Similarities: Belongs to the IAP family.

    分子量
    33 kDa
    基因ID
    79444
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