BIRC7 抗体 (AA 87-298)
Quick Overview for BIRC7 抗体 (AA 87-298) (ABIN3043512)
抗原
See all BIRC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 87-298
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原理
- Anti-Livin/BIRC7 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Livin/BIRC7 Antibody (ABIN3043512). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Livin recombinant protein (Position: E87-S298). Human Livin shares 69.8% amino acid (aa) sequence identity with mouse Livin.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, -
ELISA, 0.1-0.5 μg/mL, -
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Expression and clinical significance of livin protein in hepatocellular carcinoma." in: Disease markers, Vol. 35, Issue 5, pp. 489-96, (2014) (PubMed).
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: "Expression and clinical significance of livin protein in hepatocellular carcinoma." in: Disease markers, Vol. 35, Issue 5, pp. 489-96, (2014) (PubMed).
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- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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别名
- BIRC7
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背景
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Synonyms: Baculoviral IAP repeat-containing protein 7,6.3.2.-,Kidney inhibitor of apoptosis protein,KIAP,Livin,Melanoma inhibitor of apoptosis protein,ML-IAP,RING finger protein 50,Baculoviral IAP repeat-containing protein 7 30 kDa subunit,Truncated livin,p30-Livin,tLivin,BIRC7,KIAP, LIVIN, MLIAP, RNF50,UNQ5800/PRO19607/PRO21344,
Tissue Specificity: Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.
Background: Baculoviral IAP repeat-containing protein 7 is a protein that in humans is encoded by the BIRC7 gene. This protein is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) and a RING finger motif. Its gene is mapped to 20q13.3. It has got 280- and 298- amino acids. The protein is highly expressed in melanomas while lowly expressed in some lymphomas, fetal kidney, fetal liver, testis and thymus. BIRC7 plays a vital role in blocking apoptosis induced.
Sequence Similarities: Belongs to the IAP family.
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分子量
- 33 kDa
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基因ID
- 79444
抗原
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