BIRC3 抗体 (AA 1-191)
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北京 101111
Quick Overview for BIRC3 抗体 (AA 1-191) (ABIN3043510)
抗原
See all BIRC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-191
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原理
- Anti-cIAP2/BIRC3 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-cIAP2/BIRC3 Antibody (ABIN3043510). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human cIAP2 recombinant protein (Position: M1-K191). Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.
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亚型
- IgG
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anti-Baculoviral IAP Repeat Containing 3 (BIRC3) antibody
BIRC3 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-180) antibodyBIRC3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 59-88), (N-Term) antibodyBIRC3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB34025 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 76-245) antibodyBIRC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (Internal Region) antibodyVerified BIRC3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 255-529) antibodyBIRC3 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 101-131), (N-Term) antibodyBIRC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2213 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 101-131) antibodyBIRC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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别名
- BIRC3
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背景
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Synonyms: Baculoviral IAP repeat-containing protein 3,6.3.2.-,Apoptosis inhibitor 2,API2,C-IAP2,IAP homolog C,Inhibitor of apoptosis protein 1,IAP-1,hIAP-1,hIAP1,RING finger protein 49,TNFR2-TRAF-signaling complex protein 1,BIRC3,API2, IAP1, MIHC, RNF49,
Tissue Specificity: Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.
Background: Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Sequence Similarities: Belongs to the IAP family.
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分子量
- 68 kDa
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基因ID
- 330
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UniProt
- Q13489
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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