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BIRC3 抗体 (AA 1-191)

This anti-BIRC3 antibody is a 兔 多克隆 antibody detecting BIRC3 in WB. Suitable for 人.
产品编号 ABIN3043510
发货至: 中国

Quick Overview for BIRC3 抗体 (AA 1-191) (ABIN3043510)

抗原

See all BIRC3 抗体
BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

适用

  • 60
  • 22
  • 5
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宿主

  • 54
  • 6
  • 1

克隆类型

  • 55
  • 6
多克隆

标记

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This BIRC3 antibody is un-conjugated

应用范围

  • 50
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  • 1
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Western Blotting (WB)
  • 抗原表位

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    AA 1-191

    原理

    Anti-cIAP2/BIRC3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-cIAP2/BIRC3 Antibody Picoband® (ABIN3043510). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human cIAP2 recombinant protein (Position: M1-K191). Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human
    1. "Entrez Gene: BIRC3 baculoviral IAP repeat-containing 3". 2. Liston P, Roy N, Tamai K, Lefebvre C, Baird S, Cherton-Horvat G, Farahani R, McLean M, Ikeda JE, MacKenzie A, Korneluk RG (February 1996). "Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes". Nature 379 (6563): 349-53. 3. Rothe M, Pan MG, Henzel WJ, Ayres TM, Goeddel DV (February 1996). "The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins". Cell 83 (7): 1243-52.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

    别名

    BIRC3

    背景

    Synonyms: Baculoviral IAP repeat-containing protein 3,6.3.2.-,Apoptosis inhibitor 2,API2,C-IAP2,IAP homolog C,Inhibitor of apoptosis protein 1,IAP-1,hIAP-1,hIAP1,RING finger protein 49,TNFR2-TRAF-signaling complex protein 1,BIRC3,API2, IAP1, MIHC, RNF49,

    Tissue Specificity: Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.

    Background: Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

    Sequence Similarities: Belongs to the IAP family.

    分子量

    68 kDa

    基因ID

    330

    UniProt

    Q13489

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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