Cyclin D3 抗体 (AA 136-292)
Quick Overview for Cyclin D3 抗体 (AA 136-292) (ABIN3043485)
抗原
See all Cyclin D3 (CCND3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 136-292
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原理
- Anti-Cyclin D3/CCND3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cyclin D3/CCND3 Antibody Picoband® (ABIN3043485). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cyclin D3 recombinant protein (Position: Q136-L292). Human Cyclin D3 shares 94% and 93% amino acid (aa) sequences identity with mouse and rat Cyclin D3, respectively.
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亚型
- IgG
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anti-Cyclin D3 (CCND3) (AA 1-292) antibody
CCND3 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (pThr283) antibodyCCND3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 136-292) antibodyCCND3 适用: 人, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 121-220) antibodyCCND3 适用: 人, 兔 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (C-Term) antibodyCCND3 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) (C-Term) antibodyCCND3 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D3 (CCND3) antibodyCCND3 适用: 人 WB, IF (cc) 宿主: 兔 Monoclonal 4A8 unconjugated
anti-Cyclin D3 (CCND3) (AA 1-292) antibodyCCND3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Inaba T, Matsushime H, Valentine M, Roussel MF, Sherr CJ, Look AT (August 1992). "Genomic organization, chromosomal localization, and independent expression of human cyclin D genes". Genomics 13 (3): 565-74. 2. Beltran AL, Ordonez JL, Otero AP, Blanca A, Sevillano V, Sanchez-Carbayo M, Kirkali Z, Cheng L, Montironi R, Prieto R, De Alava E. Fluorescence in situ hybridization analysis of CCND3 gene as marker of progression in bladder carcinoma. J Biol Regul Homeost Agents. 2013 Apr-Jun, 27(2):559-67. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cyclin D3 (CCND3)
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别名
- CCND3
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背景
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Synonyms: G1/S-specific cyclin-D3,CCND3,
Background: CCND3, also called Cyclin D3, is a protein that in humans is encoded by the CCND3 gene. It is mapped to 6p21.1. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. In addition, overexpression of CCND3 upregulated the translational activity in HeLa cells in a dose-dependent manner.
Sequence Similarities: Belongs to the cyclin family. Cyclin D subfamily.
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分子量
- 33 kDa
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基因ID
- 896
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UniProt
- P30281
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
抗原
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