MCAM 抗体 (AA 59-401)
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北京 101111
Quick Overview for MCAM 抗体 (AA 59-401) (ABIN3043466)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-401
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原理
- Anti-CD146/MCAM Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human CD146 shares 73% amino acid (aa) sequence identity with both mouse,rat CD146.
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产品特性
- Anti-CD146/MCAM Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD146 recombinant protein (Position: H59-A401). Human CD146 shares 73% amino acid (aa) sequence identity with both mouse and rat CD146.
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亚型
- IgG
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anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 84-189) antibody
MCAM 适用: 人 IHC, FACS, WB, ELISA 宿主: 小鼠 Monoclonal 6C3E6 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 50-646) antibodyMCAM 适用: 人 FACS, WB, IF, ELISA 宿主: 小鼠 Monoclonal 4D10C7 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 447-646) antibodyMCAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 59-401) antibodyMCAM 适用: 人 IHC, FACS, WB, IHC (fro) 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 27-621) antibodyMCAM 适用: 小鼠, 大鼠 IHC, FACS, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) antibodyMCAM 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 226-374) antibodyMCAM 适用: 人 IHC 宿主: 小鼠 Monoclonal MCAM-3046 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人 IHC, FACS, WB, IF, ELISA 宿主: 兔 Monoclonal 8A10 unconjugated Recombinant Antibody
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyKD Validated MCAM 适用: 人 FACS, WB 宿主: 兔 Monoclonal 23GB2705 unconjugated Recombinant Antibody
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- MCAM
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背景
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Background: CD146 (cluster of differentiation 146), also known as the melanoma cell adhesion molecule (MCAM) or cell surface glycoprotein MUC18, is a 113 kDa cell adhesion molecule currently used as a marker for endothelial cell lineage. MCAM, a member of the immunoglobulin superfamily, is homologous to several cell adhesion molecules and is associated with tumor progression and the development of metastasis in human malignant melanoma. By radiation hybrid analysis, this gene is mapped to chromosome 11q23.3. MCAM has been demonstrated to appear on a small subset of T and B lymphocytes in the peripheral blood of healthy individuals. MCAM has been seen as a marker for mesenchymal stem cells isolated from multiple adult and fetal organs, and its expression may be linked to multipotency mesenchymal stem cells with greater differentiation potential express higher levels of MCAM on the cell surface.
Gene Full Name: melanoma cell adhesion molecule
Sequence Similarities: Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
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分子量
- 120 kDa
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基因ID
- 4162
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UniProt
- P43121
抗原
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