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MCAM 抗体 (AA 447-646)

MCAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6143621
发货至: 中国
  • 抗原 See all MCAM 抗体
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    抗原表位
    • 16
    • 13
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 447-646
    适用
    • 127
    • 48
    • 47
    • 15
    • 14
    • 9
    • 9
    • 8
    • 6
    • 2
    宿主
    • 95
    • 56
    • 1
    • 1
    • 1
    • 1
    克隆类型
    • 86
    • 69
    多克隆
    标记
    • 75
    • 14
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCAM antibody is un-conjugated
    应用范围
    • 91
    • 72
    • 65
    • 44
    • 20
    • 19
    • 18
    • 12
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    序列
    VLNLSCEASG HPRPTISWNV NGTASEQDQD PQRVLSTLNV LVTPELLETG VECTASNDLG KNTSILFLEL VNLTTLTPDS NTTTGLSTST ASPHTRANST STERKLPEPE SRGVVIVAVI VCILVLAVLG AVLYFLYKKG KLPCRRSGKQ EITLPPSRKS ELVVEVKSDK LPEEMGLLQG SSGDKRAPGD QGEKYIDLRH
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 447-646 of human CD146/CD146/MCAM (NP_006491.2).
    亚型
    IgG
    Top Product
    Discover our top product MCAM Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    别名
    MCAM (MCAM 产品)
    别名
    CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
    背景
    Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.,MCAM,CD146,MUC18,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,MCAM
    分子量
    57 kDa/71 kDa
    基因ID
    4162
    UniProt
    P43121
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