PDK4 抗体 (N-Term)
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Quick Overview for PDK4 抗体 (N-Term) (ABIN3043461)
抗原
See all PDK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 91-125, N-Term
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原理
- Anti-PDK4 Antibody
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序列
- WYIQSLMDLV EFHEKSPDDQ KALSDFVDTL IKVRN
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PDK4 Antibody (ABIN3043461). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human PDK4, different from the related mouse and rat sequences by three amino acids.
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亚型
- IgG
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 382-410), (C-Term) antibody
PDK4 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB03041 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 117-387) antibodyPDK4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 382-410) antibodyPDK4 适用: 人, 小鼠 WB, IHC, ELISA, IF, mIHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 102-411) antibodyPDK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 83-111) antibodyPDK4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 1-411) antibodyPDK4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (N-Term) antibodyPDK4 适用: 人, 小鼠, 大鼠, 马, Pig, 兔, Cow, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 143-333) antibodyPDK4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 1-411) antibodyPDK4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (C-Term) antibodyPDK4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
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别名
- PDK4
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背景
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Synonyms: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial,2.7.11.2,Pyruvate dehydrogenase kinase isoform 4,PDK4,PDHK4,
Tissue Specificity: Ubiquitous, highest levels of expression in heart and skeletal muscle. .
Background: Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. In addition, PDK4 is increased in hibernation and helps to decrease metabolism and conserve glucose by decreasing its conversion to acetyl-CoA, which enters the citric acid cycle and is converted to ATP.
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分子量
- 46 kDa
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基因ID
- 5166
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UniProt
- Q16654
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途径
- PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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