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PDK4 抗体 (N-Term)

This anti-PDK4 antibody is a 兔多克隆 antibody detecting PDK4 in WB. Suitable for 人和大鼠.

Western Blotting (WB) image for anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 91-125), (N-Term) antibody (ABIN3043461) (PDK4 抗体 (N-Term))

1 image

产品编号 ABIN3043461

发货至: 中国

Quick Overview for PDK4 抗体 (N-Term) (ABIN3043461)

抗原

See all PDK4 抗体

PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

适用

75
48
7
2
2
2
1
1
1
1
1

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

48
7
4
4
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This PDK4 antibody is un-conjugated

应用范围

70
41
30
13
13
9
9
8
6
3
2
1
1
1

Western Blotting (WB)

Discover our top product PDK4 Primary Antibody

抗原表位
15

9

8

7

6

5

5

3

2

2

2

1

1

1

1

1

1

1
AA 91-125, N-Term

原理

Anti-PDK4 Antibody Picoband®

序列

WYIQSLMDLV EFHEKSPDDQ KALSDFVDTL IKVRN

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-PDK4 Antibody Picoband® (ABIN3043461). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human PDK4, different from the related mouse and rat sequences by three amino acids.

亚型

IgG
anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 382-410), (C-Term) antibody
PDK4 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB03041 unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 117-387) antibody
PDK4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 382-410) antibody
PDK4 适用: 人, 小鼠 WB, IHC, ELISA, IF, mIHC 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 102-411) antibody
PDK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 83-111) antibody
PDK4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 1-411) antibody
PDK4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (N-Term) antibody
PDK4 适用: 人, 小鼠, 大鼠, 马, Pig, 兔, Cow, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 143-333) antibody
PDK4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (AA 1-411) antibody
PDK4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) (N-Term) antibody
PDK4 适用: 人, 马, Pig, 兔, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: PDK4 pyruvate dehydrogenase kinase, isozyme 4". 2. Andrews MT, Squire TL, Bowen CM, Rollins MB (Jul 1998). "Low-temperature carbon utilization is regulated by novel gene activity in the heart of a hibernating mammal". Proceedings of the National Academy of Sciences of the United States of America 95 (14): 8392-7. 3. Gudi R, Bowker-Kinley MM, Kedishvili NY, Zhao Y, Popov KM (Dec 1995). "Diversity of the pyruvate dehydrogenase kinase gene family in humans".The Journal of Biological Chemistry 270 (48): 28989-94.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

别名

PDK4

背景

Synonyms: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial,2.7.11.2,Pyruvate dehydrogenase kinase isoform 4,PDK4,PDHK4,
Tissue Specificity: Ubiquitous, highest levels of expression in heart and skeletal muscle. .
Background: Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. In addition, PDK4 is increased in hibernation and helps to decrease metabolism and conserve glucose by decreasing its conversion to acetyl-CoA, which enters the citric acid cycle and is converted to ATP.

分子量

46 kDa

基因ID

5166

UniProt

Q16654

途径

PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect

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