MUC5AC 抗体 (AA 4848-5030)
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- 抗原 See all MUC5AC 抗体
- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
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抗原表位
- AA 4848-5030
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MUC5AC antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Mucin-5AC(MUC5AC) detection. Tested with WB, IHC-P in Human.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Mucin-5AC(MUC5AC) detection. Tested with WB, IHC-P in Human.
Gene Name: mucin 5AC, oligomeric mucus/gel-forming
Protein Name: Mucin-5AC - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Mucin 5AC recombinant protein (Position: D4848-H5030).
- 亚型
- IgG
- Top Product
- Discover our top product MUC5AC Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Mucin 5AC is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2." in: Molecular and cellular biochemistry, Vol. 377, Issue 1-2, pp. 75-85, (2013) (PubMed).
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Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2." in: Molecular and cellular biochemistry, Vol. 377, Issue 1-2, pp. 75-85, (2013) (PubMed).
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- 抗原
- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
- 别名
- MUC5AC (MUC5AC 产品)
- 别名
- MUC5 antibody, TBM antibody, leB antibody, 2210005L13Rik antibody, MGM antibody, mucin 5AC, oligomeric mucus/gel-forming antibody, putative gastric mucin antibody, mucin 5, subtypes A and C, tracheobronchial/gastric antibody, mucin 2, oligomeric mucus/gel-forming antibody, MUC5AC antibody, Smp_144070 antibody, Muc5ac antibody, MUC2 antibody
- 背景
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Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. MUC5AC is also a direct and critical mediator of resistance during intestinal nematode infection.
Synonyms: Apomucin antibody|Gastric mucin antibody|LeB antibody|Lewis B blood group antigen antibody|Major Airway Glycoprotein antibody|MUC 5 antibody|MUC5 antibody|MUC5AC antibody|Mucin 5 subtype AC tracheobronchial antibody|Mucin 5 Subtypes A And C antibody|Mucin 5 subtypes A and C tracheobronchial/gastric antibody|Mucin 5AC antibody|Mucin 5AC oligomeric mucus/gel forming antibody|Mucin 5AC, oligomeric mucus/gel forming pseudogene antibody|TBM antibody|Tracheobronchial Mucin antibody - 基因ID
- 4586
- UniProt
- P98088
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