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LIM Domain Kinase 1 抗体 (C-Term)

Name: LIM Domain Kinase 1 抗体 (C-Term)
SKU: ABIN3043411
Availability: OutOfStock

This anti-LIM Domain Kinase 1 antibody is a 兔多克隆 antibody detecting LIM Domain Kinase 1 in WB. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Western Blotting (WB) image for anti-LIM Domain Kinase 1 (LIMK1) (AA 599-634), (C-Term) antibody (ABIN3043411) (LIM Domain Kinase 1 抗体 (C-Term))

1 image

(1 reference)

产品编号 ABIN3043411

发货至: 中国

Datasheet as PDF

Quick Overview for LIM Domain Kinase 1 抗体 (C-Term) (ABIN3043411)

抗原

See all LIM Domain Kinase 1 (LIMK1) 抗体

LIM Domain Kinase 1 (LIMK1)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This LIM Domain Kinase 1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product LIMK1 Primary Antibody

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AA 599-634, C-Term

原理

Anti-LIMK1 Antibody Picoband®

序列

KLEHWLETLR MHLAGHLPLG PQLEQLDRGF WETYRR

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-LIMK1 Antibody Picoband® (ABIN3043411). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human LIMK1 , different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

亚型

IgG
anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibody
LIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-LIM Domain Kinase 1 (LIMK1) antibody
LIMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3H6 unconjugated

anti-LIM Domain Kinase 1 (LIMK1) antibody
LIMK1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 6B4 unconjugated

anti-LIM Domain Kinase 1 (LIMK1) (AA 451-550) antibody
LIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibody
LIMK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B2 unconjugated

anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibody
LIMK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated

anti-LIM Domain Kinase 1 (LIMK1) (AA 548-647) antibody
LIMK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated

anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibody
LIMK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-LIM Domain Kinase 1 (LIMK1) (pThr508) antibody
LIMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-LIM Domain Kinase 1 (LIMK1) (AA 1-647) antibody
LIMK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: LIMK1 LIM domain kinase 1". 2. Osborne LR, Martindale D, Scherer SW, Shi XM, Huizenga J, Heng HH, Costa T, Pober B, Lew L, Brinkman J, Rommens J, Koop B, Tsui LC (Jan 1997). "Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients". Genomics 36 (2): 328-36. 3. Tassabehji M, Metcalfe K, Fergusson WD, Carette MJ, Dore JK, Donnai D, Read AP, Pröschel C, Gutowski NJ, Mao X, Sheer D (Aug 1996). "LIM-kinase deleted in Williams syndrome". Nat. Genet. 13 (3): 272-3.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Zhang, Gan, Zhou: "Immunohistochemical investigation of the correlation between LIM kinase 1 expression and development and progression of human ovarian carcinoma." in: The Journal of international medical research, Vol. 40, Issue 3, pp. 1067-73, (2013) (PubMed).
抗原

LIM Domain Kinase 1 (LIMK1)

别名

LIMK1

背景

Synonyms: LIM domain kinase 1,LIMK-1,2.7.11.1,LIMK1,LIMK,
Tissue Specificity: Highest expression in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
Background: LIM domain kinase 1?is an?enzyme?that in humans is encoded by the?LIMK1?gene. There are approximately 40 known eukaryotic LIM proteins, so named for the?LIM domains?they contain. LIM domains are highly conserved?cysteine-rich structures containing 2?zinc fingers. Although zinc fingers usually function by binding to?DNA?or?RNA, the LIM motif probably mediates?protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2?N-terminal?LIM motifs, a central?PDZ domain, and a?C-terminal?protein kinase?domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development.

分子量

72 kDa

基因ID

3984

UniProt

P53667

途径

Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events