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SERPINB2 抗体 (AA 1-180)

SERPINB2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043329
发货至: 中国
  • 抗原 See all SERPINB2 抗体
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    抗原表位
    • 14
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 1-180
    适用
    • 42
    • 12
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 7
    • 1
    • 1
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINB2 antibody is un-conjugated
    应用范围
    • 24
    • 18
    • 12
    • 12
    • 10
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-SerpinB2 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-SerpinB2 Antibody Picoband® (ABIN3043329). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human SerpinB2 recombinant protein (Position: M1-K180). Human SerpinB2 shares 70% and 66% amino acid (aa) sequence identity with mouse and rat SerpinB2, respectively.
    亚型
    IgG
    Top Product
    Discover our top product SERPINB2 Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Corsetti JP, et al. Plasminogen activator inhibitor-2 polymorphism associates with recurrent coronary event risk in patients with high HDL and C-reactive protein levels. PLoS One, 2013. 2. Huang Z, et al. SERPINB2 down-regulation contributes to chemoresistance in head and neck cancer. Mol Carcinog, 2014 Oct. 3. Jin Y, et al. Expression of plasminogen activator inhibitor-2 is negatively associated with invasive potential in hepatocellular carcinoma cells. Chin Med Sci J, 2013 Mar. 4. Zhou L, et al. Low expression of PAI-2 as a novel marker of portal vein tumor thrombosis and poor prognosis in hepatocellular carcinoma. World J Surg, 2013 Mar.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    别名
    SERPINB2 (SERPINB2 产品)
    物质类
    Amino Acid
    背景

    Synonyms: Plasminogen activator inhibitor 2,PAI-2,Monocyte Arg-serpin,Placental plasminogen activator inhibitor,Serpin B2,Urokinase inhibitor,SERPINB2,PAI2, PLANH2,

    Tissue Specificity: Plasma. .

    Background: SERPINB2 is also known as PAI or PAI2. Plasminogen activator inhibitor-2 (placental PAI) is acoagulation factor that inactivates tPA and urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2 exists in two forms, a 60- kDa extracellular glycosylated form and a 43- kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed PAI-2 remains unsecreted due to the presence of an inefficient internal signal peptide.

    Sequence Similarities: Belongs to the semaphorin family.

    分子量
    47 kDa
    基因ID
    5055
    UniProt
    P05120
    途径
    Autophagy
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