Prostate Specific Antigen 抗体 (AA 25-261)
Quick Overview for Prostate Specific Antigen 抗体 (AA 25-261) (ABIN3043283)
抗原
See all Prostate Specific Antigen (PSA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-261
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原理
- Anti-Prostate Specific Antigen/KLK3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Prostate Specific Antigen/KLK3 Antibody Picoband® (ABIN3043283). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.
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亚型
- IgG
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anti-Prostate Specific Antigen (PSA) (AA 1-100) antibody
PSA 适用: 人 IHC, WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Prostate Specific Antigen (PSA) (AA 26-251) antibodyPSA 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5A11E2 unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal A67-B-E3 unconjugated
anti-Prostate Specific Antigen (PSA) (AA 39-261) antibodyPSA 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 IHC, WB, IHC (p), FACS, ICC, IHC (fro), ELISpot 宿主: 小鼠 Monoclonal C3F12 unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 IHC, StM, ISt 宿主: 兔 Monoclonal KLK3-2871R unconjugated Recombinant Antibody
anti-Prostate Specific Antigen (PSA) (AA 150-250) antibodyPSA 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-603R unconjugated Recombinant Antibody
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人, 兔 ELISA, WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal Pa3 unconjugated
anti-Prostate Specific Antigen (PSA) antibodyPSA 适用: 人 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal PA5 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human
1. Balk SP, Ko YJ, Bubley GJ (January 2003). "Biology of prostate-specific antigen". J. Clin. Oncol. 21 (2): 383-91. 2. Catalona, W. J., Richie, J. P., Ahmann, F. R., Hudson, M. A., Scardino, P. T., Flanigan, R. C., Dekernion, J. B., Ratliff, T. L., Kavoussi, L. R., Dalkin, B. L. (1994). "Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: Results of a multicenter clinical trial of 6,630 men". The Journal of urology 151 (5): 1283-1290. 3. Lilja H (November 2003). "Biology of prostate-specific antigen". Urology 62 (5 Suppl 1): 27-33. doi:10.1016/S0090-4295(03)00775-1. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Prostate Specific Antigen (PSA)
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别名
- KLK3
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背景
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Synonyms: Prostate-specific antigen,PSA,3.4.21.77,Gamma-seminoprotein,Seminin,Kallikrein-3,P-30 antigen,Semenogelase,KLK3,APS,
Tissue Specificity: Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level). Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells. .
Background: Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. KLK3 is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. KLK3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.
Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.
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分子量
- 29 kDa
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基因ID
- 354
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UniProt
- P07288
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途径
- Complement System
抗原
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