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Nibrin 抗体 (C-Term)

Name: Nibrin 抗体 (C-Term)
SKU: ABIN3043282
Availability: OutOfStock

NBN 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Nibrin (NBN) (AA 714-745), (C-Term) antibody (ABIN3043282) (Nibrin 抗体 (C-Term))

Anti-p95 NBS1 Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (Nibrin 抗体 (C-Term))

IHC

IHC analysis of p95 NBS1 using anti-p95 NBS1 antibody . (Nibrin 抗体 (C-Term))

IHC

5 images

产品编号 ABIN3043282

发货至: 中国

Datasheet as PDF

抗原 See all Nibrin (NBN) 抗体

Nibrin (NBN)
抗原表位
37

15

11

8

7

5

5

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 714-745, C-Term
适用
101

61

35

2

1

1

1

1
人, 小鼠, 大鼠
宿主
120

15
兔
Compatible Secondaries
克隆类型
108

27
多克隆
标记
69

8

6

6

6

6

6

6

5

3

2

2

2

2

2

2

2
This Nibrin antibody is un-conjugated
应用范围
106

45

30

27

26

26

25

18

12

11

6

4

2

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Nibrin(NBN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

序列

RKNTELEEWL RQEMEVQNQH AKEESLADDL FR

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Nibrin(NBN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: nibrin
Protein Name: Nibrin

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human p95 NBS1 (714-745aa RKNTELEEWLRQEMEVQNQHAKEESLADDLFR), different from the related mouse sequence by three amino acids, and from the related rat sequence by five amino acids.

亚型

IgG

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anti-Nibrin (NBN) (AA 435-754) antibody
NBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 645-754) antibody
NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
抗原

Nibrin (NBN)

别名

NBN (NBN 产品)

别名

NBN antibody, AT-V1 antibody, AT-V2 antibody, ATV antibody, NBS antibody, NBS1 antibody, P95 antibody, Nbs1 antibody, im:6911679 antibody, zgc:194152 antibody, nibrin antibody, NBN antibody, nbn antibody, Nbn antibody

背景

P95 NBS1, also known as NBN or Nibrin, is a protein which in humans is encoded by the NBN gene. Nibrin is a protein associated with the repair of double strand breaks (DSBs) which pose serious damage to a genome. It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50(N/M/R, more commonly referred to asMRN) double strand DNA break repair complex. This complex recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci. It also has a role in regulation of N/M/R (MRN) protein complex activity which includes end-processing of both physiological and mutagenic DNA double strand breaks (DSBs).

Synonyms: AT V1 antibody|AT V2 antibody|ATV antibody|ATV antibody|Cell cycle regulatory protein p95 antibody|FLJ10155 antibody|MGC87362 antibody|NBN antibody|NBN_HUMAN antibody|NBS 1 antibody|NBS antibody|NBS antibody|NBS1 antibody|Nibrin antibody|Nibrin antibody| Nijmegen breakage syndrome 1 (nibrin) antibody|Nijmegen breakage syndrome antibody|Nijmegen breakage syndrome protein 1 antibody|p95 antibody|p95 antibody|p95 protein of the MRE11/RAD50 complex antibody

基因ID

4683

UniProt

O60934

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response