Sonic Hedgehog 抗体 (N-Term)
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- 抗原 See all Sonic Hedgehog (SHH) 抗体
- Sonic Hedgehog (SHH)
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抗原表位
- AA 203-218, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Sonic Hedgehog antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-Sonic Hedgehog/SHH Antibody Picoband®
- 序列
- ATVHLEQGGT KLVKDL
- 交叉反应 (详细)
- No cross-reactivity with other proteins
- 产品特性
- Anti-Sonic Hedgehog/SHH Antibody (ABIN3043230). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Sonic Hedgehog, identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product SHH Primary Antibody
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Tsukurov, O., Boehmer, A., Flynn, J., Nicolai, J.-P., Hamel, B. C. J., Traill, S., Zaleske, D., Mankin, H. J., Yeon, H., Ho, C., Tabin, C., Seidman, J. G., Seidman, C. : A complex bilateral polysyndactyly disease locus maps to chromosome 7q36. Nature Genet. 6: 282-286, 1994. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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Sonic hedgehog expression correlates with distant metastasis in pancreatic adenocarcinoma." in: Pancreas, Vol. 40, Issue 2, pp. 233-6, (2011) (PubMed).
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Sonic hedgehog expression correlates with distant metastasis in pancreatic adenocarcinoma." in: Pancreas, Vol. 40, Issue 2, pp. 233-6, (2011) (PubMed).
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- 抗原
- Sonic Hedgehog (SHH)
- 别名
- SHH (SHH 产品)
- 背景
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Synonyms: Sonic hedgehog protein,SHH,HHG-1,Sonic hedgehog protein N-product,Sonic hedgehog protein C-product,SHH,
Tissue Specificity: Expressed in fetal intestine, liver, lung, and kidney. Not expressed in adult tissues.
Background: The mouse, chicken, and zebrafish Shh homologs are highly conserved. SHH expression was not detected in adult tissues examined. However, it was expressed in fetal intestine, liver, lung, and kidney. SHH gene is mapped to 7q. SHH mutations are not a frequent cause of isolated oral clefts.
Sequence Similarities: Belongs to the hedgehog family.
- 分子量
- 62-65 kDa
- UniProt
- Q15465
- 途径
- Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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