Laminin gamma 1 抗体 (C-Term)
(14 references)-
- 抗原 See all Laminin gamma 1 (LAMC1) 抗体
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
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抗原表位
- AA 1566-1579, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Laminin gamma 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Laminin subunit gamma-1(LAMC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- KKQEAAIMDY NRDI
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Laminin subunit gamma-1(LAMC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: laminin, gamma 1(formerly LAMB2)
Protein Name: Laminin subunit gamma-1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Laminin gamma 1(1566-1579aa KKQEAAIMDYNRDI), different from the related mouse sequence by one amino acid and rat sequence by three amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product LAMC1 Primary Antibody
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anti-Laminin, gamma 1 (LAMC1) antibody
LAMC1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1300-1609) antibodyLAMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (all Isoforms) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal M1 unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1442-1552) antibodyLAMC1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 521-772) antibodyLAMC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1333-1607) antibodyLAMC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyLAMC1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL3195 unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6-B4 unconjugated
anti-Laminin, gamma 1 (LAMC1) (N-Term) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "Engineering blood vessels through micropatterned co-culture of vascular endothelial and smooth muscle cells on bilayered electrospun fibrous mats with pDNA inoculation." in: Acta biomaterialia, Vol. 11, pp. 114-25, (2014) (PubMed).
: "Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 8, pp. 4827-36, (2014) (PubMed).
: "Comparison of morphology and biocompatibility of acellular nerve scaffolds processed by different chemical methods." in: Journal of materials science. Materials in medicine, Vol. 25, Issue 5, pp. 1283-91, (2014) (PubMed).
: "Three dimensional chitosan scaffolds influence the extra cellular matrix expression in Schwann cells." in: Materials science & engineering. C, Materials for biological applications, Vol. 42, pp. 474-8, (2014) (PubMed).
: "Highly effective ex vivo gene manipulation to study kidney development using self-complementary adenoassociated viruses." in: TheScientificWorldJournal, Vol. 2014, pp. 682189, (2014) (PubMed).
: "Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart." in: Development, growth & differentiation, Vol. 56, Issue 4, pp. 276-92, (2014) (PubMed).
: "Promoted regeneration of mature blood vessels by electrospun fibers with loaded multiple pDNA-calcium phosphate nanoparticles." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fu?r Pharmazeutische Verfahrenstechnik e.V, Vol. 85, Issue 3 Pt A, pp. 699-710, (2013) (PubMed).
: "Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-?1/Smad signaling pathway, thereby leading to anti-fibrotic effect." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 20, Issue 13, pp. 1172-9, (2013) (PubMed).
: "In vitro culture of tumour-derived hepatocytes in decellularised whole-liver biological scaffolds." in: Digestion, Vol. 87, Issue 3, pp. 189-95, (2013) (PubMed).
: "Anti-fibrotic effects of puerarin on CCl4-induced hepatic fibrosis in rats possibly through the regulation of PPAR-? expression and inhibition of PI3K/Akt pathway." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 56, pp. 436-42, (2013) (PubMed).
: "Transcriptome sequencing reveals differences between primary and secondary hair follicle-derived dermal papilla cells of the Cashmere goat (Capra hircus)." in: PLoS ONE, Vol. 8, Issue 9, pp. e76282, (2013) (PubMed).
: "Multiple release of polyplexes of plasmids VEGF and bFGF from electrospun fibrous scaffolds towards regeneration of mature blood vessels." in: Acta biomaterialia, Vol. 8, Issue 7, pp. 2659-69, (2012) (PubMed).
: "Microplasmin degrades fibronectin and laminin at vitreoretinal interface and outer retina during enzymatic vitrectomy." in: Current eye research, Vol. 34, Issue 12, pp. 1057-64, (2009) (PubMed).
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: "Remarkable preservation of Ca(2+) homeostasis and inhibition of apoptosis contribute to anti-muscle atrophy effect in hibernating Daurian ground squirrels." in: Scientific reports, Vol. 6, pp. 27020, (2018) (PubMed).
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- 抗原
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
- 别名
- LAMC1 (LAMC1 产品)
- 别名
- lamb2 antibody, Lamb2 antibody, B2e antibody, sly antibody, LAMB2 antibody, putative laminin gamma-1 chain antibody, laminin subunit gamma 1 antibody, laminin, gamma 1 antibody, Smp_163810 antibody, lamc1 antibody, Lamc1 antibody, LAMC1 antibody
- 背景
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Laminin gamma1, Laminin subunit gamma-1, is a protein that in humans is encoded by the LAMC1 gene. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma(formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly though to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs(5.5 and 7.5 kb) seen on Northern analysis.
Synonyms: LAMB2 antibody|LAMC1 antibody|LAMC1_HUMAN antibody|Laminin B2 chain antibody|Laminin subunit gamma-1 antibody|Laminin, gamma 1(formerly LAMB2) antibody|Laminin-1 subunit gamma antibody|Laminin-10 subunit gamma antibody|Laminin-11 subunit gamma antibody|Laminin-2 subunit gamma antibody|Laminin-3 subunit gamma antibody|Laminin-4 subunit gamma antibody|Laminin-6 subunit gamma antibody|Laminin-7 subunit gamma antibody|Laminin-8 subunit gamma antibody|Laminin-9 subunit gamma antibody|MGC87297 antibody|S-LAM gamma antibody|S-laminin subunit gamma antibody - UniProt
- P11047
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