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Kallikrein 1 抗体 (Middle Region)

Name: Kallikrein 1 抗体 (Middle Region)
SKU: ABIN3043141
Availability: OutOfStock

This anti-Kallikrein 1 antibody is a 兔多克隆 antibody detecting Kallikrein 1 in WB 和 IHC. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 2+ publications.

Anti-Kallikrein 1 antibody, Western blotting Lane 1: Recombinant Human KLK1 Protein 10ng Lane 2: Recombinant Human KLK1 Protein 5ng Lane 3: Recombinant Human KLK1 Protein 2. (Kallikrein 1 抗体 (Middle Region))

Anti-Kallikrein 1 antibody, IHC(P) IHC(P): Human Pancreatic Cancer Tissue (Kallikrein 1 抗体 (Middle Region))

IHC

2 images

(2 references)

产品编号 ABIN3043141

发货至: 中国

Quick Overview for Kallikrein 1 抗体 (Middle Region) (ABIN3043141)

抗原

See all Kallikrein 1 (KLK1) 抗体

Kallikrein 1 (KLK1)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Kallikrein 1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product KLK1 Primary Antibody

抗原表位
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1
AA 182-197, Middle Region

原理

Anti-Kallikrein 1/KLK1 Antibody Picoband®

序列

NDECKKAHVQ KVTDFM

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Kallikrein 1/KLK1 Antibody (ABIN3043141). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human Kallikrein 1.

亚型

IgG
anti-Kallikrein 1 (KLK1) (AA 25-262) antibody
KLK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 25-261) antibody
KLK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 27-261) antibody
KLK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 25-262) antibody
KLK1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 101-200) antibody
KLK1 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 35-276) antibody
KLK1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 1-262) antibody
KLK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 1-262) antibody
KLK1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (Internal Region) antibody
KLK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Kallikrein 1 (KLK1) (AA 243-261), (C-Term) antibody
KLK1 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
1. Azizi, M., Boutouyrie, P., Bissery, A., Agharazii, M., Verbeke, F., Stern, N., Bura-Riviere, A., Laurent, S., Alhenc-Gelas, F., Jeunemaitre, X. Arterial and renal consequences of partial genetic deficiency in tissue kallikrein activity in humans. J. Clin. Invest. 115: 780-787, 2005. 2. Baker, A. R., Shine, J. Human kidney kallikrein: cDNA cloning and sequence analysis. DNA 4: 445-450, 1985. 3. Clements J, Hooper J, Dong Y, Harvey T (2001). "The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions".

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Zhang, Xu, Zhao, Chen: "Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).

Lin, Lin, Chung, Vonderfecht, Camden, Flodby, Borok, Limesand, Mizushima, Ann: "Dynamic involvement of ATG5 in cellular stress responses." in: Cell death & disease, Vol. 5, pp. e1478, (2014) (PubMed).
抗原

Kallikrein 1 (KLK1)

别名

KLK1

背景

Synonyms: Kallikrein-1,3.4.21.35,Kidney/pancreas/salivary gland kallikrein,Tissue kallikrein,KLK1,
Tissue Specificity: Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84. .
Background: KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

分子量

29 kDa

UniProt

P06870

途径

Complement System