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Kallikrein 1 抗体 (C-Term)

KLK1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043080
发货至: 中国
  • 抗原 See all Kallikrein 1 (KLK1) 抗体
    Kallikrein 1 (KLK1)
    抗原表位
    • 16
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 243-261, C-Term
    适用
    • 56
    • 25
    • 21
    小鼠
    宿主
    • 60
    • 6
    • 2
    克隆类型
    • 65
    • 3
    多克隆
    标记
    • 31
    • 10
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Kallikrein 1 antibody is un-conjugated
    应用范围
    • 35
    • 25
    • 24
    • 18
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Kallikrein-1(KLK1) detection. Tested with WB, IHC-P in Mouse.
    序列
    YTRVLNFNTW IRETMAEND
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Kallikrein-1(KLK1) detection. Tested with WB, IHC-P in Mouse.
    Gene Name: kallikrein 1
    Protein Name: Kallikrein-1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 1(243-261aa YTRVLNFNTWIRETMAEND).
    亚型
    IgG
    Top Product
    Discover our top product KLK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Zhang, Xu, Zhao, Chen: "Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).

    Lin, Lin, Chung, Vonderfecht, Camden, Flodby, Borok, Limesand, Mizushima, Ann: "Dynamic involvement of ATG5 in cellular stress responses." in: Cell death & disease, Vol. 5, pp. e1478, (2014) (PubMed).

  • 抗原
    Kallikrein 1 (KLK1)
    别名
    KLK1 (KLK1 产品)
    别名
    KLKR antibody, Klk6 antibody, hK1 antibody, klkr antibody, kallikrein antibody, 0610007D04Rik antibody, Kal antibody, Klk1b6 antibody, mGk-6 antibody, kallikrein 1 antibody, kallikrein 1 L homeolog antibody, KLK1 antibody, klk1.L antibody, LOC100101620 antibody, Klk1 antibody
    背景
    KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

    Synonyms: Glandular kallikrein 1 antibody|hK 1 antibody|hK1 antibody|Kallikrein serine protease 1 antibody|Kallikrein-1 antibody|Kidney/pancreas/salivary gland kallikrein antibody|Klk 6 antibody|KLK1 antibody|KLK1_HUMAN antibody|Klk6 antibody|KLKR antibody|Tissue kallikrein antibody
    UniProt
    P15947
    途径
    Complement System
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