CYGB 抗体 (N-Term)
Quick Overview for CYGB 抗体 (N-Term) (ABIN3043127)
抗原
See all CYGB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-68, N-Term
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原理
- Anti-Cytoglobin/CYGB Antibody Picoband®
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序列
- FVNFPSAKQY FSQFKHMED
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Cytoglobin/CYGB Antibody (ABIN3043127). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Cytoglobin, identical to the related rat sequence, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Cytoglobin (CYGB) (AA 1-190) antibody
CYGB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytoglobin (CYGB) (AA 87-132) antibodyCYGB 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3A5-2D2 unconjugated
anti-Cytoglobin (CYGB) (AA 1-190) antibodyCYGB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Asahina, K., Kawada, N., Kristensen, D. B., Nakatani, K., Seki, S., Shiokawa, M., Tateno, C., Obara, M., Yoshizato, K. Characterization of human stellate cell activation-associated protein and its expression in human liver. Biochim. Biophys. Acta 1577: 471-475, 2002. 2. Burmester, T., Ebner, B., Weich, B., Hankeln, T. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Molec. Biol. Evol. 19: 416-421, 2002. 3. Geuens, E., Brouns, I., Flamez, D., Dewilde, S., Timmermans, J.-P., Moens, L. A globin in the nucleus! J. Biol. Chem. 278: 30417-30420, 2003. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CYGB (Cytoglobin (CYGB))
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别名
- CYGB
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背景
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Synonyms: Cytoglobin,Histoglobin,HGb,Stellate cell activation-associated protein,CYGB,STAP,
Tissue Specificity: Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. .
Background: Cytoglobin (CYGB), also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The cytoglobin gene is mapped on 17q25.1. The CYGB gene contains 4 exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir by Sawai et al.
Sequence Similarities: Belongs to the APP family.
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分子量
- 21 kDa
抗原
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