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BDNF 抗体 (N-Term)

BDNF 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043096
发货至: 中国
  • 抗原 See all BDNF 抗体
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    抗原表位
    • 16
    • 15
    • 11
    • 10
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 129-148, N-Term
    适用
    • 117
    • 57
    • 55
    • 14
    • 10
    • 10
    • 9
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    人, 大鼠, 小鼠
    宿主
    • 111
    • 26
    • 4
    • 3
    • 2
    • 2
    克隆类型
    • 115
    • 32
    多克隆
    标记
    • 85
    • 17
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BDNF antibody is un-conjugated
    应用范围
    • 116
    • 49
    • 48
    • 31
    • 26
    • 25
    • 18
    • 13
    • 13
    • 12
    • 9
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Brain-derived neurotrophic factor(BDNF) detection. Tested with WB in Human,Mouse,Rat.
    序列
    HSDPARRGEL SVCDSISEWV
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Brain-derived neurotrophic factor(BDNF) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: brain-derived neurotrophic factor
    Protein Name: Brain-derived neurotrophic factor(BDNF)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminal of human BDNF(129-148aa HSDPARRGELSVCDSISEWV), identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product BDNF Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Yin, Liang, Wang, Yan, Yin, Wu, Su: "Naringenin induces laxative effects by upregulating the expression levels of c-Kit and SCF, as well as those of aquaporin 3 in mice with loperamide-induced constipation." in: International journal of molecular medicine, Vol. 41, Issue 2, pp. 649-658, (2018) (PubMed).

    Li, Wu, Miao, Xiong et al.: "Effects of Polysaccharide of Gastrodia Elata Blume and Electro-Acupuncture on Expressions of Brain-Derived Neurotrophic Factor and Stem Cell Factor Protein in Caudate Putamen of Focal Cerebral ..." in: Medical science monitor basic research, Vol. 22, pp. 175-180, (2017) (PubMed).

    Zheng, Lu, Guo, Zhang, Liu, Guo, Huang, Han: "Electroacupuncture Ameliorates Learning and Memory and Improves Synaptic Plasticity via Activation of the PKA/CREB Signaling Pathway in Cerebral Hypoperfusion." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 7893710, (2016) (PubMed).

    Tong, Wang, Li, Zhu, Chen, Hua: "Effects of senescence on the expression of BDNF and TrkB receptor in the lateral geniculate nucleus of cats." in: Dong wu xue yan jiu = Zoological research, Vol. 36, Issue 1, pp. 48-53, (2015) (PubMed).

    Zhao, Chen, Shen, Zhao, Wang, Shi, Wang, Cui, Yan, Xue: "Transplantation of human umbilical cord blood mesenchymal stem cells to treat a rat model of traumatic brain injury." in: Neural regeneration research, Vol. 7, Issue 10, pp. 741-8, (2015) (PubMed).

    Tan, Shi, Shi, Liu, Liu, Wang, Chen, Xing, Shen, Jia, Ye, He, Li: "Changes in compressed neurons from dogs with acute and severe cauda equina constrictions following intrathecal injection of brain-derived neurotrophic factor-conjugated polymer nanoparticles." in: Neural regeneration research, Vol. 8, Issue 3, pp. 233-43, (2014) (PubMed).

    Li, Li, Li, Quan, Wang: "Cellular and molecular mechanisms underlying the action of ginsenoside Rg1 against Alzheimer's disease." in: Neural regeneration research, Vol. 7, Issue 36, pp. 2860-6, (2014) (PubMed).

    Wang, Feng, Fu, Li: "Panax notoginsenoside Rb1 ameliorates Alzheimer's disease by upregulating brain-derived neurotrophic factor and downregulating Tau protein expression." in: Experimental and therapeutic medicine, Vol. 6, Issue 3, pp. 826-830, (2013) (PubMed).

    Li, Xia, Zhang, Wu: "S100B protein, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in human milk." in: PLoS ONE, Vol. 6, Issue 6, pp. e21663, (2011) (PubMed).

    Shi, Shao, Yuan, Pan, Li: "Acute stress and chronic stress change brain-derived neurotrophic factor (BDNF) and tyrosine kinase-coupled receptor (TrkB) expression in both young and aged rat hippocampus." in: Yonsei medical journal, Vol. 51, Issue 5, pp. 661-71, (2010) (PubMed).

  • 抗原
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    别名
    BDNF (BDNF 产品)
    别名
    ANON2 antibody, BULN2 antibody, bdnf-A antibody, BDNF antibody, bdnf antibody, brain derived neurotrophic factor antibody, brain-derived neurotrophic factor antibody, brain-derived neurotrophic factor L homeolog antibody, brain-derived neurotrophic factor S homeolog antibody, BDNF antibody, Bdnf antibody, bdnf antibody, bdnf.L antibody, bdnf.S antibody
    背景
    Brain derived neurotrophic factor(BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields. BDNF has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.

    Synonyms: Abrineurin antibody|BDNF antibody|BDNF_HUMAN antibody|Brain Derived Neurotrophic Factor antibody|Brain-derived neurotrophic factor antibody|MGC34632 antibody|Neurotrophin antibody
    UniProt
    P23560
    途径
    RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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