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STAT5A 抗体 (C-Term)

Name: STAT5A 抗体 (C-Term)
SKU: ABIN3043020
Availability: OutOfStock

Cited in 2+ publications. The 兔多克隆 anti-STAT5A antibody (ABIN3043020) specifically detects STAT5A in WB 和 FACS. The antibody is reactive with 人, 小鼠和大鼠 samples.

Anti-STAT5a antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: COLO320 Cell Lysate Lane 3: JURKAT Cell Lysate Lane 4: CEM Cell Lysate (STAT5A 抗体 (C-Term))

1 image

(2 references)

产品编号 ABIN3043020

发货至: 中国

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Quick Overview for STAT5A 抗体 (C-Term) (ABIN3043020)

抗原

See all STAT5A 抗体

STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This STAT5A antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS)

Discover our top product STAT5A Primary Antibody

抗原表位
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C-Term

原理

Anti-STAT5a Antibody

序列

YNMYPQNPDH VLDQDGE

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-STAT5a Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human STAT5a.

亚型

IgG
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 6E5 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 583-794) antibody
STAT5A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D4 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-794) antibody
STAT5A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 744-794) antibody
STAT5A 适用: 人, 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR124H unconjugated Recombinant Antibody

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-104) antibody
STAT5A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B12 unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody
KD Validated STAT5A 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB1920 unconjugated Recombinant Antibody

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 635-794) antibody
STAT5A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pTyr694) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." in: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).
抗原

STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

别名

STAT5A

背景

Background: STAT5 (Signal transducer and activator of transcription 5) also known as STAT5A, MGF, is a protein that serve the dual function of signal transducers and activators of transcription in cells exposed to signaling polypeptides. Hou et al. (1995) cloned the human STAT5 cDNA from an umbilical vein endothelial cell library and found that it encodes a 794-amino acid polypeptide with a predicted mass of approximately 90.5 kD. To analyze the possible role of STAT5 in human GH-induced proliferation, Friedrichsen et al. (2001) expressed a dominant-negative STAT5 mutant, STAT5A-delta-749, in INS-1 cells under the control of a doxycycline-inducible promoter by stable transfection. Chromatin immunoprecipitation analysis confirmed binding of STAT5 to the HIF2A promoter 344 bp upstream of the HIF2A start site. STAT5 overexpression independently resulted in erythroid commitment in megakaryocytic-erythroid progenitors, which was abrogated by knockdown of GATA1. STAT5 is responsible for the immediate-early induction of the long isoform of the BCL2-related protein in erythroid cells through binding to the promoter of the BCLX gene.
Gene Full Name: signal transducer and activator of transcription 5A
Sequence Similarities: Belongs to the transcription factor STAT family.

分子量

95 kDa

基因ID

6776

UniProt

P42229

途径

JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation