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OSBP 抗体 (Middle Region)

OSBP 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042983
发货至: 中国
  • 抗原 See all OSBP 抗体
    OSBP (Oxysterol Binding Protein (OSBP))
    抗原表位
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 290-304, Middle Region
    适用
    • 20
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 16
    • 3
    • 1
    克隆类型
    • 17
    • 3
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    This OSBP antibody is un-conjugated
    应用范围
    • 15
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Oxysterol-binding protein 1(OSBP) detection. Tested with WB in Human,Mouse,Rat.
    序列
    WQKSLQYERD QRIRL
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Oxysterol-binding protein 1(OSBP) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: oxysterol binding protein
    Protein Name: Oxysterol-binding protein 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human OSBP1(290-304aa WQKSLQYERDQRIRL), identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product OSBP Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    OSBP (Oxysterol Binding Protein (OSBP))
    别名
    OSBP (OSBP 产品)
    别名
    CG6708 antibody, Dmel\\CG6708 antibody, OSBP-Dm antibody, osbp antibody, OSBP1 antibody, 1110018F06Rik antibody, AW559088 antibody, mKIAA4220 antibody, Oxysterol binding protein antibody, oxysterol binding protein antibody, Osbp antibody, OSBP antibody
    背景
    OSBP(Oxysterol-Binding Protein), also called OSBP1, is a protein that in humans is encoded by the OSBP gene. Im et al.(2005) reported the structure of the full-length yeast oxysterol-binding-protein Osh4, a member of the OSBP-related protein(ORP) family, at 1.5- to 1.9-angstrom resolution in complexes with ergosterol, cholesterol, and 7-, 20- and 25-hydroxy cholesterol. Moreira et al.(2001) refined the localization of the OSBP1 gene to chromosome 11q12.1 by radiation hybrid analysis. Wang et al.(2005) found that OSBP functions as a cholesterol-binding scaffolding protein coordinating the activity of 2 phosphatases to control the extracellular signal-regulated kinase(ERK) signaling pathway. Cytosolic OSBP formed an approximately 440-kD oligomer with a member of the PTPPBS family of tyrosine phosphatases, the serine/threonine phosphatase PP2A, and cholesterol.

    Synonyms: OSBP 1 antibody|OSBP antibody|OSBP1_HUMAN antibody|Oxysterol binding protein 1 antibody|Oxysterol-binding protein 1 antibody
    UniProt
    P22059
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