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FLT1 抗体 (N-Term)

This anti-FLT1 antibody is a 兔 多克隆 antibody detecting FLT1 in WB. Suitable for 大鼠 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN3042978
发货至: 中国

Quick Overview for FLT1 抗体 (N-Term) (ABIN3042978)

抗原

See all FLT1 抗体
FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

适用

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大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FLT1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 278-298, N-Term

    原理

    Anti-VEGF Receptor 1/FLT1 Antibody Picoband®

    序列

    IRQRIDQSNP HSNVFHSVLK I

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-VEGF Receptor 1/FLT1 Antibody (ABIN3042978). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of rat FLT1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    1. Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M (May 1990). "Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family". Oncogene 5 (4): 519-24. PMID 2158038. 2. Entrez Gene: FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)". 3. He, Y., Smith, S. K., Day, K. A., Clark, D. E., Licence, D. R., Charnock-Jones, D. S.Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity.Molec. Endocr.13: 537-545, 1999.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Thimerosal, 0.01 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Liu, Kuang, Wu, Jin, Sun: "A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo." in: Scientific reports, Vol. 6, pp. 26722, (2018) (PubMed).

    Wu, You, Ma, Li, Yuan, Li, Ye, Liu, Yao, Chen, Lai, Yang: "Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice." in: PLoS ONE, Vol. 8, Issue 5, pp. e62827, (2013) (PubMed).

  • 抗原

    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

    别名

    FLT1

    背景

    Synonyms: Vascular endothelial growth factor receptor 1,VEGFR-1,2.7.10.1,Fms-like tyrosine kinase 1,FLT-1,Tyrosine-protein kinase receptor FLT,Flt1,Flt-1, Vegfr1,

    Background: Vascular endothelial growth factor receptor 1 (FLT1) is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.

    Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.

    分子量

    151 kDa

    UniProt

    P53767

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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