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BID 抗体 (C-Term)

Cited in 1 publication. This anti-BID antibody is a 兔 多克隆 antibody detecting BID in WB, IHC 和 FACS. Suitable for 小鼠 和 大鼠.
产品编号 ABIN3042950
发货至: 中国
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Quick Overview for BID 抗体 (C-Term) (ABIN3042950)

抗原

See all BID 抗体
BID (BH3 Interacting Domain Death Agonist (BID))

适用

  • 156
  • 74
  • 36
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小鼠, 大鼠

宿主

  • 168
  • 21
  • 1
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克隆类型

  • 141
  • 50
多克隆

标记

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This BID antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 20
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    AA 179-195, C-Term

    原理

    Anti-Bid Antibody

    序列

    NQNLFSYVRN LVRNEMD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Bid Antibody (ABIN3042950). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bid, different from the related rat sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat By Heat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Wang, Liu, Mi, Wang, Tang, Zhao, Li: "Sonodynamically induced apoptosis by protoporphyrin IX on hepatoma-22 cells in vitro." in: Ultrasound in medicine & biology, Vol. 36, Issue 4, pp. 667-76, (2010) (PubMed).

  • 抗原

    BID (BH3 Interacting Domain Death Agonist (BID))

    别名

    Bid

    背景

    Synonyms: BH3-interacting domain death agonist,p22 BID,BID,BH3-interacting domain death agonist p15,p15 BID,BH3-interacting domain death agonist p13,p13 BID,BH3-interacting domain death agonist p11,p11 BID,Bid,

    Tissue Specificity: Synthesized exclusively by adipocytes and secreted into plasma.

    Background: BID (BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2 family of proteins consists of both antagonists and agonists that regulate apoptosis and compete through dimerization. By fluorescence in situ hybridization, Wang et al. (1998) mapped the human BID gene to 22q11. Luo et al. (1998) reported the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as FAS and TNF.

    Sequence Similarities: Contains 1 C1q domain.

    分子量

    22 kDa

    UniProt

    P70444

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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