Kallikrein 1 抗体 (AA 25-261)
(2 references)Quick Overview for Kallikrein 1 抗体 (AA 25-261) (ABIN3042937)
抗原
See all Kallikrein 1 (KLK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-261
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原理
- Anti-Kallikrein 1/KLK1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Kallikrein 1/KLK1 Antibody (ABIN3042937). Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse KLK1 recombinant protein (Position: I25-D261).
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亚型
- IgG
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anti-Kallikrein 1 (KLK1) (AA 25-262) antibody
KLK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 25-261) antibodyKLK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 27-261) antibodyKLK1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 25-262) antibodyKLK1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 101-200) antibodyKLK1 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 35-276) antibodyKLK1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 1-262) antibodyKLK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 1-262) antibodyKLK1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (Internal Region) antibodyKLK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallikrein 1 (KLK1) (AA 243-261), (C-Term) antibodyKLK1 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse
1. Azizi, M., Boutouyrie, P., Bissery, A., Agharazii, M., Verbeke, F., Stern, N., Bura-Riviere, A., Laurent, S., Alhenc-Gelas, F., Jeunemaitre, X. Arterial and renal consequences of partial genetic deficiency in tissue kallikrein activity in humans. J. Clin. Invest. 115: 780-787, 2005. 2. Baker, A. R., Shine, J. Human kidney kallikrein: cDNA cloning and sequence analysis. DNA 4: 445-450, 1985. 3. Clements J, Hooper J, Dong Y, Harvey T (2001). "The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions". -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).
: "Dynamic involvement of ATG5 in cellular stress responses." in: Cell death & disease, Vol. 5, pp. e1478, (2014) (PubMed).
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: "Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).
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- Kallikrein 1 (KLK1)
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别名
- KLK1
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背景
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Synonyms: Kallikrein-1,3.4.21.35,Glandular kallikrein K1,KAL-B,Renal kallikrein,Tissue kallikrein-6,mGK-6,Klk1,Klk-6, Klk6,
Background: KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.
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分子量
- 29 kDa
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UniProt
- P15947
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途径
- Complement System
抗原
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