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Kallikrein 1 抗体 (AA 25-261)

Cited in 2+ publications. This 兔 多克隆 anti-Kallikrein 1 antibody specifically detects Kallikrein 1 in WB 和 IHC. The antibody is reactive with 小鼠 samples.
产品编号 ABIN3042937
发货至: 中国
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Quick Overview for Kallikrein 1 抗体 (AA 25-261) (ABIN3042937)

抗原

See all Kallikrein 1 (KLK1) 抗体
Kallikrein 1 (KLK1)

适用

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  • 28
小鼠

宿主

  • 61
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  • 1

克隆类型

  • 65
  • 3
多克隆

标记

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This Kallikrein 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 6
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    AA 25-261

    原理

    Anti-Kallikrein 1/KLK1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Kallikrein 1/KLK1 Antibody (ABIN3042937). Tested in IHC, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse KLK1 recombinant protein (Position: I25-D261).

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse
    Western blot, 0.1-0.5 μg/mL, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Zhang, Xu, Zhao, Chen: "Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).

    Lin, Lin, Chung, Vonderfecht, Camden, Flodby, Borok, Limesand, Mizushima, Ann: "Dynamic involvement of ATG5 in cellular stress responses." in: Cell death & disease, Vol. 5, pp. e1478, (2014) (PubMed).

  • 抗原

    Kallikrein 1 (KLK1)

    别名

    KLK1

    背景

    Synonyms: Kallikrein-1,3.4.21.35,Glandular kallikrein K1,KAL-B,Renal kallikrein,Tissue kallikrein-6,mGK-6,Klk1,Klk-6, Klk6,

    Background: KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

    Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

    分子量

    29 kDa

    UniProt

    P15947

    途径

    Complement System
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